Spatial and single-cell transcriptomics decipher the cellular environment containing HLA-G+ cancer cells and SPP1+ macrophages in colorectal cancer

Yuki Ozato, Yasuhiro Kojima, Yuta Kobayashi, +34

Cell Reports

ImmunologyPathologyCrc CellsCancer BiologySpatial Omics +16

Direct Reprogramming Improves Cardiac Function and Reverses Fibrosis in Chronic Myocardial Infarction

Hidenori Tani, Taketaro Sadahiro, Yu Yamada, +14

Circulation

Mechanisms of action and resistance in histone methylation-targeted therapy

Makoto Yamagishi, Yuta Kuze, Seiichiro Kobayashi, +21

Nature

Chronological genome and single-cell transcriptome integration characterizes the evolutionary process of adult T cell leukemia-lymphoma

Makoto Yamagishi, Miyuki Kubokawa, Yuta Kuze, +10

Nature Communications

Genomic profiling reveals heterogeneous populations of ductal carcinoma in situ of the breast

Satoi Nagasawa, Yuta Kuze, Ichiro Maeda, +16

Communications Biology

Spatial and single-cell colocalisation analysis reveals MDK-mediated immunosuppressive environment with regulatory T cells in colorectal carcinogenesis

Masahiro Hashimoto, Yasuhiro Kojima, Takeharu Sakamoto, +40

EBioMedicine

Spatially resolved gene expression profiling of tumor microenvironment reveals key steps of lung adenocarcinoma development

Yuma Takano, Jun Suzuki, Kotaro Nomura, +19

Nature Communications

Cardiac Reprogramming and Gata4 Overexpression Reduce Fibrosis and Improve Diastolic Dysfunction in Heart Failure With Preserved Ejection Fraction

Yu Yamada, Taketaro Sadahiro, Koji Nakano, +19

Circulation

Identification of Galectin-7 as a crucial metastatic enhancer of squamous cell carcinoma associated with immunosuppression

Jianbo An, Yushi Nagaki, Satoru Motoyama, +9

Oncogene

Crucial Metastatic EnhancerTumor BiologySquamous Cell CarcinomaMedicineImmunology +7

Genomic profiling reveals heterogeneous populations of ductal carcinoma in situ of the breast

Satoi Nagasawa, Yuta Kuze, Ichiro Maeda, +16