Daily Treatment with SMTC1100, a Novel Small Molecule Utrophin Upregulator, Dramatically Reduces the Dystrophic Symptoms in the mdx Mouse

Jonathon M. Tinsley, Rebecca J. Fairclough, Richard Storer, +11

PLoS ONE

Multiple pathological events in exercised dystrophic mdx mice are targeted by pentoxifylline: outcome of a large array of in vivo and ex vivo tests

Rosa Burdi, Jean‐François Rolland, B. Fraysse, +13

Journal of Applied Physiology

Muscle FunctionPathologyNeuromusculoskeletal DisorderCellular PhysiologyNeuromuscular Blockade +18

Enalapril treatment discloses an early role of angiotensin II in inflammation- and oxidative stress-related muscle damage in dystrophic mdx mice

Anna Cozzoli, Beatrice Nico, Valeriana Sblendorio, +6

Pharmacological Research

Cardiovascular PharmacologyPharmacotherapyDystrophic Mdx MiceOxidative StressInflammation +22

Ryanodine channel complex stabilizer compound S48168/ARM210 as a disease modifier in dystrophin‐deficient <i>mdx</i> mice: proof‐of‐concept study and independent validation of efficacy

Roberta Francesca Capogrosso, Paola Mantuano, Kitipong Uaesoontrachoon, +15

The FASEB Journal

GLPG0492, a novel selective androgen receptor modulator, improves muscle performance in the exercised-mdx mouse model of muscular dystrophy

Anna Cozzoli, Roberta Francesca Capogrosso, Valeriana Sblendorio, +5

Pharmacological Research

Molecular PharmacologyMuscle FunctionKinesiologyMolecular PhysiologyEndocrine Mechanism +9

Gene expression in mdx mouse muscle in relation to age and exercise: aberrant mechanical–metabolic coupling and implications for pre-clinical studies in Duchenne muscular dystrophy

Giulia Maria Camerino, Maria Cannone, Arcangela Giustino, +4

Human Molecular Genetics

Contractile efficiency of dystrophic mdx mouse muscle: in vivo and ex vivo assessment of adaptation to exercise of functional end points

Roberta Francesca Capogrosso, Paola Mantuano, Anna Cozzoli, +11

Journal of Applied Physiology

Gentamicin treatment in exercised mdx mice: Identification of dystrophin-sensitive pathways and evaluation of efficacy in work-loaded dystrophic muscle

Annamaria De Luca, Beatrice Nico, Jean‐François Rolland, +12

Neurobiology of Disease

Work-loaded Dystrophic MuscleMuscle FunctionMuscle InjurySkeletal MuscleExercise Physiology +8

Evaluation of potential synergistic action of a combined treatment with alpha-methyl-prednisolone and taurine on the mdx mouse model of Duchenne muscular dystrophy

Anna Cozzoli, Jean‐François Rolland, Roberta Francesca Capogrosso, +5

Neuropathology and Applied Neurobiology

Effect of a long-term treatment with metformin in dystrophic mdx mice: A reconsideration of its potential clinical interest in Duchenne muscular dystrophy

Paola Mantuano, Francesca Sanarica, Elena Conte, +10

Biochemical Pharmacology

Neurodegenerative DiseasesDuchenne Muscular DystrophyMedicinePhysiologyLong-term Treatment +4