Jacob A. Boyer

Senolytic CAR T cells reverse senescence-associated pathologies

Corina Amor, Judith Feucht, Josef Leibold et al. · Nature · 2020 · 968 citations · Full text

T-regulatory Cell, Immunology, Cellular Senescence +5

P-selectin-targeted nanocarriers induce active crossing of the blood–brain barrier via caveolin-1-dependent transcytosis

Daniel Tylawsky, Hiroto Kiguchi, Jake Vaynshteyn et al. · Nature Materials · 2023 · 185 citations · Full text

Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction

Corina Amor, Inés Fernández-Maestre, Saria Chowdhury et al. · Nature Aging · 2024 · 148 citations · Full text

Anti-aging, Aging, T-regulatory Cell +21

Regulation of PTEN translation by PI3K signaling maintains pathway homeostasis

Radha Mukherjee, Kiran Vanaja, Jacob A. Boyer et al. · Molecular Cell · 2021 · 128 citations · Full text

Signal Transduction, Signaling Pathway, Molecular Pathway +10

Selective inhibitors of mTORC1 activate 4EBP1 and suppress tumor growth

Bianca J. Lee, Jacob A. Boyer, G. Leslie Burnett et al. · Nature Chemical Biology · 2021 · 74 citations · Full text

Tumor Biology, Medicine, Pharmacology +6