Interaction of endosialin/TEM1 with extracellular matrix proteins mediates cell adhesion and migration

Brian Tomkowicz, Katherine A. Rybinski, Brian Foley, +7

Proceedings of the National Academy of Sciences

Collagen TypesCell AdhesionImmunologyMolecular BiologyCell Junctions +20

Endosialin/TEM-1/CD248 regulates pericyte proliferation through PDGF receptor signaling

Brian Tomkowicz, Denise Sebeck, Philip M. Sass, +3

Cancer Biology & Therapy

Pdgf-bb StimulationSignal TransductionSignaling PathwayTumor MicroenvironmentCell Regulation +13

TIM-3 Suppresses Anti-CD3/CD28-Induced TCR Activation and IL-2 Expression through the NFAT Signaling Pathway

Brian Tomkowicz, Eileen S. Walsh, Adam Cotty, +9

PLoS ONE

Nfat Signaling PathwayImmunologyImmune RegulationImmunologic MechanismCd4 T Cell Responses +23

An arrestin-dependent multi-kinase signaling complex mediates MIP-1β/CCL4 signaling and chemotaxis of primary human macrophages

Ricky Cheung, Mobeen Malik, Vipa Ravyn, +3

Journal of Leukocyte Biology

HIV-1 gp120-induced TNF-α production by primary human macrophages is mediated by phosphatidylinositol-3 (PI-3) kinase and mitogen-activated protein (MAP) kinase pathways

ChuHee Lee, Brian Tomkowicz, Bruce D. Freedman, +1

Journal of Leukocyte Biology

Characterization of the Human Folate Receptor Alpha Via Novel Antibody-Based Probes

Daniel J. O’Shannessy, Elizabeth B. Somers, Earl F. Albone, +9

Oncotarget

The Src kinase Lyn is required for CCR5 signaling in response to MIP-1β and R5 HIV-1 gp120 in human macrophages

Brian Tomkowicz, ChuHee Lee, Vipa Ravyn, +3

Blood

Monocyte Migration and LFA-1-Mediated Attachment to Brain Microvascular Endothelia Is Regulated by SDF-1α through Lyn Kinase

Mobeen Malik, Yingyu Chen, Martha Kienzle, +3

The Journal of Immunology

ImmunologyImmunologic MechanismImmunotherapyCellular PhysiologyCerebral Vascular Regulation +22

Integrin inhibition through Lyn-dependent cross talk from CXCR4 chemokine receptors in normal human CD34+ marrow cells

Yuji Nakata, Brian Tomkowicz, Alan M. Gewirtz, +1

Blood

Functional Role of Residues Corresponding to Helical Domain II (Amino Acids 35 to 46) of Human Immunodeficiency Virus Type 1 Vpr

Satya P. Singh, Brian Tomkowicz, Derhsing Lai, +5

Journal of Virology