Structure of cohesin subcomplex pinpoints direct shugoshin-Wapl antagonism in centromeric cohesion

Kodai Hara, Ge Zheng, Qianhui Qu, +5

Nature Structural & Molecular Biology

Pattern FormationCentromeric CohesionCell AdhesionMolecular BiologyCytoskeleton +3

Crystal Structure of Human REV7 in Complex with a Human REV3 Fragment and Structural Implication of the Interaction between DNA Polymerase ζ and REV1

Kodai Hara, Hiroshi Hashimoto, Yoshiki Murakumo, +7

Journal of Biological Chemistry

Structural Basis of Recruitment of DNA Polymerase ζ by Interaction between REV1 and REV7 Proteins

Sotaro Kikuchi, Kodai Hara, Toshiyuki Shimizu, +2

Journal of Biological Chemistry

Structure of a Novel DNA-binding Domain of Helicase-like Transcription Factor (HLTF) and Its Functional Implication in DNA Damage Tolerance

Asami Hishiki, Kodai Hara, Yuzu Ikegaya, +4

Journal of Biological Chemistry

Dna Damage ToleranceCrystal StructureNovel Dna-binding DomainHiran DomainGenetics +17

Crystallographic Structures of Two Bisphosphonate:1-Deoxyxylulose-5-Phosphate Reductoisomerase Complexes

Shunsuke Yajima, Kodai Hara, John M. Sanders, +5

Journal of the American Chemical Society

EngineeringSulfate IonMolecular BiologyFosmidomycin Phosphonate-binding SiteChemical Biology +14

Structure of 1-deoxy-<scp>D</scp>-xylulose 5-phosphate reductoisomerase in a quaternary complex with a magnesium ion, NADPH and the antimalarial drug fosmidomycin

Shunsuke Yajima, Kodai Hara, D. Iino, +4

Acta Crystallographica Section F Structural Biology and Crystallization Communications

Crystal StructureMolecular BiologyChemical BiologyEnzymatic ModificationRedox Biology +14

Catalytic mechanism and endo-to-exo selectivity reversion of an octalin-forming natural Diels–Alderase

Michio Sato, Shinji Kishimoto, Mamoru Yokoyama, +9

Nature Catalysis

EngineeringBiochemistryEndo-to-exo Selectivity ReversionNatural SciencesBiocatalysis +7

Dynamic feature of mitotic arrest deficient 2–like protein 2 (MAD2L2) and structural basis for its interaction with chromosome alignment–maintaining phosphoprotein (CAMP)

Kodai Hara, Shota Taharazako, Masanori Ikeda, +9

Journal of Biological Chemistry

Mad2l2 StructureMolecular BiologyCytoskeletonCell CycleProtein 2 +18

The Transcription Factor TFII-I Promotes DNA Translesion Synthesis and Genomic Stability

Farjana Fattah, Kodai Hara, Kazi R. Fattah, +7

PLoS Genetics

GeneticsGenomic MechanismMolecular BiologyMolecular GeneticsTls Deficiency +22

Identification of the first small-molecule inhibitor of the REV7 DNA repair protein interaction

Marcelo Actis, Nigus D. Ambaye, Benjamin J. Evison, +9

Bioorganic & Medicinal Chemistry

First Small-molecule InhibitorGenome InstabilityNatural SciencesOligonucleotideDna Replication +4