Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients

Jérôme Hadjadj, Nader Yatim, Laura Barnabei, +27

Science

Angiopoietin-2 as a marker of endothelial activation is a good predictor factor for intensive care unit admission of COVID-19 patients

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Angiogenesis

Impaired type I interferon activity and exacerbated inflammatory responses in severe Covid-19 patients

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ImmunodeficienciesImmunologySevere Covid-19 PatientsImmune SystemCovid-19 +17

Inhibition of the dipeptidyl peptidase DPP4 (CD26) reveals IL-33-dependent eosinophil-mediated control of tumor growth

Clémence Hollande, Jérémy Boussier, James Ziai, +13

Nature Immunology

InflammationCytokineMedicineTumor GrowthImmunology +7

Dicer-2-Dependent Generation of Viral DNA from Defective Genomes of RNA Viruses Modulates Antiviral Immunity in Insects

Enzo Z. Poirier, Bertsy Goić, Lorena Tomé-Poderti, +15

Cell Host & Microbe

Viral DnaViral ReplicationMolecular VirologyInsect VirusDefective Genomes +9

Thymic regulatory T cell niche size is dictated by limiting IL-2 from antigen-bearing dendritic cells and feedback competition

Brian M. Weist, Nadia S. Kurd, Jérémy Boussier, +2

Nature Immunology

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Attenuation of RNA viruses by redirecting their evolution in sequence space

Gonzalo Moratorio, Rasmus Henningsson, Cyril Barbezange, +10

Nature Microbiology

BiologyViral ReplicationViral EvolutionSequence SpaceNatural Sciences +9

VEXAS syndrome is characterized by inflammasome activation and monocyte dysregulation

Olivier Kosmider, Céline Posseme, Marie Templé, +31

Nature Communications

Platelet activation in critically ill COVID-19 patients

Nader Yatim, Jérémy Boussier, Richard Chocron, +18

Annals of Intensive Care

Bystander hyperactivation of preimmune CD8+ T cells in chronic HCV patients

Cécile Alanio, Francesco Nicoli, Philippe Sultanik, +20

eLife