Takuo Tsukuda

CH5424802, a Selective ALK Inhibitor Capable of Blocking the Resistant Gatekeeper Mutant

Hiroshi Sakamoto, Toshiyuki Tsukaguchi, Sayuri Hiroshima et al. · Cancer Cell · 2011 · 625 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

Host sphingolipid biosynthesis as a target for hepatitis C virus therapy

Hiroshi Sakamoto, Koichi Okamoto, Masahiro Aoki et al. · Nature Chemical Biology · 2005 · 176 citations · Full text

Life Sciences, Biochemistry, Infectious Diseases +14

Design and synthesis of a highly selective, orally active and potent anaplastic lymphoma kinase inhibitor (CH5424802)

Kazutomo Kinoshita, Kohsuke Asoh, Noriyuki Furuichi et al. · Bioorganic & Medicinal Chemistry · 2011 · 164 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +8

9-Substituted 6,6-Dimethyl-11-oxo-6,11-dihydro-5<i>H</i>-benzo[<i>b</i>]carbazoles as Highly Selective and Potent Anaplastic Lymphoma Kinase Inhibitors

Kazutomo Kinoshita, Takamitsu Kobayashi, Kohsuke Asoh et al. · Journal of Medicinal Chemistry · 2011 · 84 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Self-Enhancement of Hepatitis C Virus Replication by Promotion of Specific Sphingolipid Biosynthesis

Yuichi Hirata, Kazutaka Ikeda, Masayuki Sudoh et al. · PLoS Pathogens · 2012 · 79 citations · Full text

Life Sciences, Microbiology, Molecular Biology +17