Concepedia

Koon-Guan Lee

KL

10

Publications

671

Citations

10

H-Index

2006

Active since

Affiliations

Agency for Science, Technology and Research(Current)

Bioprocessing Technology Institute

National University of Singapore

Singapore Immunology Network

Nanyang Technological University

Koon-Guan Lee is an author at Agency for Science, Technology and Research specializing in medicine, cell signaling, and cell biology.

Top concepts

MedicineCell BiologyCell SignalingImmunologyImmune SystemInnate ImmunityImmune RegulationImmune Cell DevelopmentInflammationImmune Function

Publications per year

2006–2021

10

Publications

10

Phospholipase Cγ2 Is Critical for Dectin-1-mediated Ca2+ Flux and Cytokine Production in Dendritic Cells

Shengli Xu, Jianxin Huo, Koon-Guan Lee et al. · Journal of Biological Chemistry · 2009 · 164 citations · Full text

Bruton's tyrosine kinase phosphorylates Toll-like receptor 3 to initiate antiviral response

Koon-Guan Lee, Shengli Xu, Zi-Han Kang et al. · Proceedings of the National Academy of Sciences · 2012 · 142 citations · Full text

Bruton’s Tyrosine Kinase Phosphorylates DDX41 and Activates Its Binding of dsDNA and STING to Initiate Type 1 Interferon Response

Koon-Guan Lee, Susana Soo-Yeon Kim, Lin Kui et al. · Cell Reports · 2015 · 99 citations · Full text

Microbial Pathogens, Molecular Regulation, Adaptive Immune System +23

Bruton's Tyrosine Kinase Separately Regulates NFκB p65RelA Activation and Cytokine Interleukin (IL)-10/IL-12 Production in TLR9-stimulated B Cells

Koon-Guan Lee, Shengli Xu, Ee-Tsin Wong et al. · Journal of Biological Chemistry · 2008 · 76 citations · Full text

Immune Activation, Tyrosine Kinase, Immunology +24

BTK Modulates p53 Activity to Enhance Apoptotic and Senescent Responses

Mohammad Althubiti, Miran Rada, Jesvin Samuel et al. · Cancer Research · 2016 · 63 citations · Full text

Apoptosis, Immunology, Cell Death +16

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