Synergy between basic fibroblast growth factor and HIV-1 Tat protein in induction of Kaposi's sarcoma

Barbara Ensoli, Rita Gendelman, Phillip D. Markham, +7

Nature

Human RetrovirusHiv-1 Tat ProteinImmunologyPathologyHiv +4

HIV protease inhibitors are potent anti-angiogenic molecules and promote regression of Kaposi sarcoma

Cecilia Sgadari, Giovanni Barillari, Elena Toschi, +14

Nature Medicine

Kaposi SarcomaHiv Protease InhibitorsMedicineImmunologyAntiviral Therapy +8

Control of SHIV-89.6P-infection of cynomolgus monkeys by HIV-1 Tat protein vaccine

Aurelio Cafaro, Antonella Caputo, C Fracasso, +16

Nature Medicine

VaccinationVaccine DevelopmentCynomolgus MonkeysHuman RetrovirusVaccine Target +6

Reactivation and persistence of human herpesvirus-8 infection in B cells and monocytes by Th-1 cytokines increased in Kaposi's sarcoma.

Paolo Monini, Sandra Colombini, Michael Stürzl, +22

PubMed

The lymphoproliferative disease of granular lymphocytes. A heterogeneous disorder ranging from indolent to aggressive conditions

Gianpietro Semenzato, Franco Pandolfi, Teodoro Chisesi, +12

Cancer

Clinical course and prognosis of the lymphoproliferative disease of granular lymphocytes. A multicenter study

Franco Pandolfi, Thomas P. Loughran, Gordon Starkebaum, +28

Cancer

Native HIV-1 Tat Protein Targets Monocyte-Derived Dendritic Cells and Enhances Their Maturation, Function, and Antigen-Specific T Cell Responses

Emanuele Fanales‐Belasio, Sonia Moretti, Filomena Nappi, +4

The Journal of Immunology

The Tat protein of human immunodeficiency virus type-1 promotes vascular cell growth and locomotion by engaging the alpha5beta1 and alphavbeta3 integrins and by mobilizing sequestered basic fibroblast growth factor.

Giovanni Barillari, Cecilia Sgadari, Valeria Fiorelli, +8

PubMed

Vaccination with DNA containing tat coding sequences and unmethylated CpG motifs protects cynomolgus monkeys upon infection with simian/human immunodeficiency virus (SHIV89.6P)

Aurelio Cafaro, Fausto Titti, C Fracasso, +19

Vaccine

VaccinationVaccine DevelopmentCynomolgus MonkeysUnmethylated Cpg MotifsHuman Retrovirus +9

Contribution of Nonneutralizing Vaccine-Elicited Antibody Activities to Improved Protective Efficacy in Rhesus Macaques Immunized with Tat/Env Compared with Multigenic Vaccines

Ruth H. Florese, Thorsten Demberg, Peng Xiao, +7

The Journal of Immunology

ImmunologyImmunodominanceHuman RetrovirusVaccine TargetChronic-phase Protection +16