Necroptosis, necrosis and secondary necrosis converge on similar cellular disintegration features

Tom Vanden Berghe, Nele Vanlangenakker, Eef Parthoens, +7

Cell Death and Differentiation

MedicinePathogenesisApoptosisPathologyCell Death +6

Macrophages use different internalization mechanisms to clear apoptotic and necrotic cells

Dmitri V. Krysko, Geertrui Denecker, Nele Festjens, +4

Cell Death and Differentiation

InflammationCytokineDifferent Internalization MechanismsGranulocyteApoptosis +11

GlycoDelete engineering of mammalian cells simplifies N-glycosylation of recombinant proteins

Leander Meuris, Francis Santens, Greg Elson, +13

Nature Biotechnology

Protein GlycosylationProtein ExpressionMedicineNatural SciencesProtein Biosynthesis +10

Ring finger protein 213 assembles into a sensor for ISGylated proteins with antimicrobial activity

Fabien Théry, Lia Martina, Caroline Asselman, +23

Nature Communications

Protein synthesis persists during necrotic cell death

Xavier Saelens, Nele Festjens, Eef Parthoens, +4

The Journal of Cell Biology

Fed-batch fermentation of GM-CSF-producing glycoengineered Pichia pastoris under controlled specific growth rate

Pieter P. Jacobs, Mehmet İnan, Nele Festjens, +5

Microbial Cell Factories

Disruption of the SapM locus in <i>Mycobacterium bovis</i> BCG improves its protective efficacy as a vaccine against <i>M. tuberculosis</i>

Nele Festjens, Pieter Bogaert, Anjana Batni, +14

EMBO Molecular Medicine

Intermediate Domain of Receptor-interacting Protein Kinase 1 (RIPK1) Determines Switch between Necroptosis and RIPK1 Kinase-dependent Apoptosis

Linde Duprez, Mathieu J.M. Bertrand, Tom Vanden Berghe, +3

Journal of Biological Chemistry

ApoptosisImmunologyImmune RegulationCell DeathIntermediate Domain +22

Characterization of genome-wide ordered sequence-tagged Mycobacterium mutant libraries by Cartesian Pooling-Coordinate Sequencing

Kristof Vandewalle, Nele Festjens, Evelyn Plets, +3

Nature Communications

The mitochondrial serine protease HtrA2/Omi cleaves RIP1 during apoptosis of Ba/F3 cells induced by growth factor withdrawal

Lieselotte Vande Walle, Ellen Wirawan, Mohamed Lamkanfi, +5

Cell Research

MitophagyMitochondrial FunctionGrowth Factor WithdrawalMedicineApoptosis +8