LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppression

Jan J. Molenaar, Raquel Domingo-Fernandéz, Marli E. Ebus, +27

Nature Genetics

Cell RegulationImmunologyLin28b InducesTumor SuppressorMedicine +3

Deep sequencing reveals differential expression of microRNAs in favorable versus unfavorable neuroblastoma

Johannes H. Schulte, Tobias Marschall, Marcel Martin, +9

Nucleic Acids Research

EngineeringGeneticsPathologyGliomaTumor Biology +14

Lysine-specific demethylase 1 restricts hematopoietic progenitor proliferation and is essential for terminal differentiation

Annika Sprüssel, Johannes H. Schulte, Susanne N. Weber, +17

Leukemia

Terminal DifferentiationDevelopmental BiologyMedicineHematologyMyeloid Neoplasia +7

Targeted Expression of Mutated ALK Induces Neuroblastoma in Transgenic Mice

Lukas C. Heukamp, Theresa Thor, Alexander Schramm, +22

Science Translational Medicine

A Cre-conditional MYCN-driven neuroblastoma mouse model as an improved tool for preclinical studies

Kristina Althoff, Anneleen Beckers, Emma Bell, +14

Oncogene

BET bromodomain protein inhibition is a therapeutic option for medulloblastoma

Anton G. Henssen, Theresa Thor, Andrea Odersky, +11

Oncotarget

MYCN and ALKF1174L are sufficient to drive neuroblastoma development from neural crest progenitor cells

Johannes H. Schulte, Scott Lindner, A Bohrer, +14

Oncogene

NeuroregenerationDevelopmental BiologyMedicineStem Cell ResearchStem Cells +4

Accurate prediction of neuroblastoma outcome based on miRNA expression profiles

Johannes H. Schulte, Benjamin Schowe, Pieter Mestdagh, +13

International Journal of Cancer

The GSK461364 PLK1 inhibitor exhibits strong antitumoral activity in preclinical neuroblastoma models

Kristian W. Pajtler, Natalie Sadowski, Sandra Ackermann, +16

Oncotarget

Preclinical Neuroblastoma ModelsCancer BiologyGliomaTumor BiologyNeuroblastoma Cell Lines +14

<scp>M</scp>i<scp>R</scp>‐34a deficiency accelerates medulloblastoma formation <i>in vivo</i>

Theresa Thor, Annette Künkele, Kristian W. Pajtler, +28

International Journal of Cancer