Synthesis, anticoagulant and PIVKA-II induced by new 4-hydroxycoumarin derivatives

Omaima M. Abdelhafez, Kamelia M. Amin, Rasha Z. Batran, +3

Bioorganic & Medicinal Chemistry

Medicinal ChemistryBioorganic ChemistryMedicineNatural SciencesPharmacotherapy +5

Novel coumarin-6-sulfonamides as apoptotic anti-proliferative agents: synthesis, <i>in vitro</i> biological evaluation, and QSAR studies

Ahmed Sabt, Omaima M. Abdelhafez, Radwan El‐Haggar, +5

Journal of Enzyme Inhibition and Medicinal Chemistry

VEGFR-2 inhibiting effect and molecular modeling of newly synthesized coumarin derivatives as anti-breast cancer agents

Eman Y. Ahmed, Nehad A. Abdel Latif, Mohamed F. El‐Mansy, +2

Bioorganic & Medicinal Chemistry

Breast OncologyMedicineBreast CancerPharmacotherapyCoumarin Derivatives +8

Design, synthesis and anticancer activity of benzofuran derivatives targeting VEGFR-2 tyrosine kinase

Omaima M. Abdelhafez, Kamelia M. Amin, Hamed I. Ali, +2

RSC Advances

Benzofuran DerivativesChemoprevention StrategyBenzofuran ScaffoldPharmacotherapyVegfr-2 Tyrosine Kinase +18

PDE6D Inhibitors with a New Design Principle Selectively Block K-Ras Activity

Farid Ahmad Siddiqui, Catharina Alam, Petja Rosenqvist, +13

ACS Omega

Molecular DockingCombinatorial ChemistryMedicinal ChemistryChaperone Pde6dDrug Target +13

Synthesis of New 7-Oxycoumarin Derivatives As Potent and Selective Monoamine Oxidase A Inhibitors

Omaima M. Abdelhafez, Kamelia M. Amin, Hamed I. Ali, +2

Journal of Medicinal Chemistry

Medicinal ChemistryPharmaceutical ScienceDerivative (Chemistry)BiochemistryMedicine +12

Design and molecular modeling of novel P38α MAPK inhibitors targeting breast cancer, synthesized from oxygen heterocyclic natural compounds

Omaima M. Abdelhafez, Eman Y. Ahmed, Nehad A. Abdel Latif, +3

Bioorganic & Medicinal Chemistry

Molecular PharmacologyBiochemistryMedicineNatural SciencesSmall Molecules +7

Monoamine oxidase A and B inhibiting effect and molecular modeling of some synthesized coumarin derivatives

Omaima M. Abdelhafez, Kamelia M. Amin, Hamed I. Ali, +2

Neurochemistry International

Synthesized Coumarin DerivativesCombinatorial ChemistryMedicinal ChemistryDerivativesBiochemistry +7

Design, synthesis and anticancer activity of furochromone and benzofuran derivatives targeting VEGFR-2 tyrosine kinase

Omaima M. Abdelhafez, Hamed I. Ali, Kamelia M. Amin, +2

RSC Advances

Molecular PharmacologyMedicinal ChemistryDrug TargetingBenzofuran DerivativesAnti-vegfr-2 Activity +13

DNA binding, antiviral activities and cytotoxicity of new furochromone and benzofuran derivatives

Omaima M. Abdelhafez, Nehad Ahmed Abedelatif, Farid A. Badria

Archives of Pharmacal Research

Dna BindingBenzofuran DerivativesBiochemistryMedicineAntiviral Drug Development +5