Efficient Liver Targeting by Polyvalent Display of a Compact Ligand for the Asialoglycoprotein Receptor

Carlos Sanhueza, Michael M. Baksh, Benjamin A. Thuma, +21

Journal of the American Chemical Society

Drug TargetMedicinal ChemistryAsialoglycoprotein ReceptorBiochemistryCompact Ligand +17

Glycomimetic Ligands for the Human Asialoglycoprotein Receptor

Sreeman Mamidyala, Sanjay Dutta, Boris A. Chrunyk, +13

Journal of the American Chemical Society

New LigandsMedicinal ChemistryHuman Asialoglycoprotein ReceptorGlycosylationBiochemistry +12

An Enantioselective Total Synthesis and Stereochemical Revision of (+)-Citrinadin B

Ke Kong, John A. Enquist, Monica E. McCallum, +4

Journal of the American Chemical Society

Bioorganic ChemistryBiochemistryNatural SciencesMedicineStereochemical Revision +10

Discovery of Potent and Orally Bioavailable Macrocyclic Peptide–Peptoid Hybrid CXCR7 Modulators

Markus Boehm, Kevin Beaumont, Rhys Jones, +25

Journal of Medicinal Chemistry

Spirolactam-Based Acetyl-CoA Carboxylase Inhibitors: Toward Improved Metabolic Stability of a Chromanone Lead Structure

David A. Griffith, Robert L. Dow, Kim Huard, +20

Journal of Medicinal Chemistry

Medicinal ChemistryChromanone Lead StructureBioorganic ChemistryPharmaceutical ChemistryBiochemistry +12

Synthesis of Spiropiperidine Lactam Acetyl-CoA Carboxylase Inhibitors

Kim Huard, Scott W. Bagley, Elnaz Menhaji‐Klotz, +12

The Journal of Organic Chemistry

Medicinal ChemistryParham-type CyclizationBiochemistryMedicineNatural Sciences +10

2,6-Disubstituted pyrazines and related analogs as NR2B site antagonists of the NMDA receptor with anti-depressant activity

Dean G. Brown, Donna L. Maier, Mark Sylvester, +30

Bioorganic & Medicinal Chemistry Letters

2,6-Disubstituted PyrazinesMolecular PharmacologyRelated AnalogsBiochemistryMedicine +7

Discovery of a Novel Small-Molecule Modulator of C–X–C Chemokine Receptor Type 7 as a Treatment for Cardiac Fibrosis

Elnaz Menhaji‐Klotz, Kevin D. Hesp, Allyn T. Londregan, +23

Journal of Medicinal Chemistry

Discovery of Diphenylacetamides as CXCR7 Inhibitors with Novel β-Arrestin Antagonist Activity

Elnaz Menhaji‐Klotz, Jessica Ward, Janice A. Brown, +6

ACS Medicinal Chemistry Letters