Classical Complement Pathway Inhibition in a “Human‐On‐A‐Chip” Model of Autoimmune Demyelinating Neuropathies

John W. Rumsey, Case Lorance, Max Jackson, +19

Advanced Therapeutics

Chronic InflammatoryImmunologyImmune RegulationImmunotherapyImmune System +17

The natural product honokiol preferentially inhibits cellular FLICE-inhibitory protein and augments death receptor–induced apoptosis

Shruti M. Raja, Shuzhen Chen, Ping Yue, +5

Molecular Cancer Therapeutics

Chemoprevention StrategyApoptosisImmunologyCell DeathNatural Product Honokiol +15

Comparative effectiveness of azathioprine and mycophenolate mofetil for myasthenia gravis (PROMISE-MG): a prospective cohort study

Pushpa Narayanaswami, Donald B. Sanders, Laine Thomas, +50

The Lancet Neurology

Mycophenolate MofetilClinical EpidemiologyClinical TrialsPharmacologyPharmacotherapy +3

Phase 1 Randomized, Double-Blind, Placebo-Controlled Study to Determine the Safety, Tolerability, and Pharmacokinetics of a Single Escalating Dose and Repeated Doses of CN-105 in Healthy Adult Subjects

Jeffrey T. Guptill, Shruti M. Raja, Felix Boakye‐Agyeman, +4

The Journal of Clinical Pharmacology

Spontaneous Intracranial HemorrhageSingle Escalating DosePharmacotherapyCerebral Vascular RegulationNeuroinflammation +22

B10 Cell Frequencies and Suppressive Capacity in Myasthenia Gravis Are Associated with Disease Severity

John S. Yi, Melissa A. Russo, Janice M. Massey, +7

Frontiers in Neurology

A Phase 1 Assessment of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of (2<i>R</i>,6<i>R</i>)‐Hydroxynorketamine in Healthy Volunteers

Shruti M. Raja, Jeffrey T. Guptill, Michelle Mack, +38

Clinical Pharmacology & Therapeutics

Psychotropic MedicationPharmacotherapyPharmacodynamic ModelingPharmacological StudyKetamine Administration +20

Dissecting the roles of DR4, DR5 and c-FLIP in the regulation of Geranylgeranyltransferase I inhibition-mediated augmentation of TRAIL-induced apoptosis

Shuzhen Chen, Lei Fu, Shruti M. Raja, +3

Molecular Cancer

Imbalance in T follicular helper cells producing IL-17 promotes pro-inflammatory responses in MuSK antibody positive myasthenia gravis

Yingkai Li, Jeffrey T. Guptill, Melissa A. Russo, +9

Journal of Neuroimmunology

InflammationCytokineAllergyAutoimmune DiseaseImmune Regulation +5

The <scp>D</scp>uke myasthenia gravis clinic registry: <scp>I</scp>. <scp>D</scp>escription and demographics

Donald B. Sanders, Shruti M. Raja, Jeffrey T. Guptill, +3

Muscle & Nerve

Perioperative Outcomes of Thymectomy in Myasthenia Gravis: A Thoracic Surgery Database Analysis

Shruti M. Raja, Jeffrey T. Guptill, Alec McConnell, +3

The Annals of Thoracic Surgery

Thoracic SurgerySurgeryPerioperative OutcomesMedicineOrthopaedic Surgery +1