Single-Cell Map of Diverse Immune Phenotypes in the Breast Tumor Microenvironment

Elham Azizi, Ambrose Carr, George Plitas, +16

Cell

Breast Tumor MicroenvironmentBreast OncologyCancer ImmunosurveillanceTumor HeterogeneityMedicine +11

High-intensity sequencing reveals the sources of plasma circulating cell-free DNA variants

Pedram Razavi, Bob T. Li, David N. Brown, +40

Nature Medicine

Dna SequencingSequencingHigh-intensity SequencingSingle Cell SequencingCell-free Dna Variants +10

Regulatory T Cells Exhibit Distinct Features in Human Breast Cancer

George Plitas, Catherine Konopacki, Kenmin Wu, +5

Immunity

Breast OncologyCancer ImmunosurveillanceT-regulatory CellImmunologyRegulatory T Cells +7

Vancomycin-resistant enterococci exploit antibiotic-induced innate immune deficits

Katharina Brandl, George Plitas, Coralia N. Mihu, +6

Nature

Health SciencesAntibioticsInnate Immune SystemImmunologyInnate Immunity +6

Pretreatment neutrophil-to-lymphocyte ratio and mutational burden as biomarkers of tumor response to immune checkpoint inhibitors

Cristina Valero, Mark Lee, Douglas R. Hoen, +26

Nature Communications

MyD88-mediated signals induce the bactericidal lectin RegIIIγ and protect mice against intestinal <i>Listeria monocytogenes</i> infection

Katharina Brandl, George Plitas, Bernd Schnabl, +2

The Journal of Experimental Medicine

How Often Does Neoadjuvant Chemotherapy Avoid Axillary Dissection in Patients With Histologically Confirmed Nodal Metastases? Results of a Prospective Study

Anita Mamtani, Andrea V. Barrio, Tari A. King, +11

Annals of Surgical Oncology

Surgical OncologyMedicineCancer ManagementSurgical PathologyBreast Cancer +5

Transient regulatory T cell ablation deters oncogene-driven breast cancer and enhances radiotherapy

Paula D. Bos, George Plitas, Dipayan Rudra, +2

The Journal of Experimental Medicine

The association between tumor mutational burden and prognosis is dependent on treatment context

Cristina Valero, Mark Lee, Douglas R. Hoen, +24

Nature Genetics

Tumor Mutational BurdenTumor HeterogeneityMedicinePathologyCancer Genomics +5

Improved prediction of immune checkpoint blockade efficacy across multiple cancer types

Diego Chowell, Seong‐Keun Yoo, Cristina Valero, +31

Nature Biotechnology

Cancer ImmunosurveillanceMedicineImmunologyMultiple Cancer TypesImmune Checkpoint Inhibitor +7