Metformin Reduces Endogenous Reactive Oxygen Species and Associated DNA Damage

Carolyn Algire, Olga Moiseeva, Xavier Deschênes‐Simard, +6

Cancer Prevention Research

Lipid PeroxidationMolecular BiologyMetabolic RemodelingType IiRedox Biology +16

Metformin blocks the stimulative effect of a high-energy diet on colon carcinoma growth in vivo and is associated with reduced expression of fatty acid synthase

Carolyn Algire, Lilian Amrein, Mahvash Zakikhani, +2

Endocrine Related Cancer

Metformin attenuates the stimulatory effect of a high-energy diet on in vivo LLC1 carcinoma growth

Carolyn Algire, Mahvash Zakikhani, M.-J. Blouin, +2

Endocrine Related Cancer

Chemoprevention StrategyStimulatory EffectControl DietPathologyMetabolic Remodeling +15

Diet and tumor LKB1 expression interact to determine sensitivity to anti-neoplastic effects of metformin in vivo

Carolyn Algire, Lilian Amrein, Miguel Bazile, +3

Oncogene

Tumor BiologyAnti-neoplastic EffectsOncologyMalignant DiseaseOncogenic Agent +6

Targeting mitochondrial complex I using BAY 87-2243 reduces melanoma tumor growth

Laura Schöckel, Andrea Glasauer, Farhan Basit, +9

Cancer & Metabolism

An AMP-activated protein kinase–stabilizing peptide ameliorates adipose tissue wasting in cancer cachexia in mice

Maria Rohm, Michaela Schäfer, Victor Laurent, +23

Nature Medicine

Cell DeathMetabolic RemodelingInsulin SignalingTumor BiologyMetabolic Syndrome +15

Similar Effects of Osmolarity, Glucose, and Phosphate on Cleavage past the 2-Cell Stage in Mouse Embryos from Outbred and F1 Hybrid Females1

Timin Hadi, Mary‐Anne Hammer, Carolyn Algire, +2

Biology of Reproduction

OocyteGeneticsMouse EmbryosReproductive BiologyEmbryology +14

TSC22D4 is a molecular output of hepatic wasting metabolism

Allan Jones, Kilian Friedrich, Maria Rohm, +15

EMBO Molecular Medicine

Metformin abolishes increased tumor¹⁸F-2-fluoro-2-deoxy-D-glucose uptake associated with a high energy diet

Haider Mashhedi, Marie‐José Blouin, Mahvash Zakikhani, +8

Cell Cycle

SIAH ubiquitin ligases regulate breast cancer cell migration and invasion independent of the oxygen status

Mohamed Adam, Sonja Matt, Sven Christian, +4

Cell Cycle

Breast OncologySiah Ubiquitin LigasesCancer BiologyTumor BiologyOncology +16