Hilary Highfield Nickols

Genetic alterations in uncommon low-grade neuroepithelial tumors: BRAF, FGFR1, and MYB mutations occur at high frequency and align with morphology

Ibrahim Qaddoumi, Wilda Orisme, Ji Wen et al. · Acta Neuropathologica · 2016 · 385 citations · Full text

Neuro-oncology, Somatic Variant, Cancer Pathology +9

Appropriate Polarization following Pharmacological Rescue of V2 Vasopressin Receptors Encoded by X-linked Nephrogenic Diabetes Insipidus Alleles Involves a Conformation of the Receptor That Also Attains Mature Glycosylation

Christopher M. Tan, Hilary Highfield Nickols, Lee E. Limbird · Journal of Biological Chemistry · 2003 · 56 citations · Full text

Design and Synthesis of an Orally Active Metabotropic Glutamate Receptor Subtype-2 (mGluR2) Positive Allosteric Modulator (PAM) That Decreases Cocaine Self-Administration in Rats

Raveendra-Panickar Dhanya, Shyama Sidique, Douglas J. Sheffler et al. · Journal of Medicinal Chemistry · 2010 · 52 citations · Full text

Partial mGlu5 Negative Allosteric Modulators Attenuate Cocaine-Mediated Behaviors and Lack Psychotomimetic-Like Effects

Robert W. Gould, Russell J. Amato, Michael Bubser et al. · Neuropsychopharmacology · 2015 · 43 citations · Full text

Psychoactive Drug, Psychiatry, Behavioral Neuroscience +12

Design and Synthesis of Systemically Active Metabotropic Glutamate Subtype-2 and -3 (mGlu_2/3) Receptor Positive Allosteric Modulators (PAMs): Pharmacological Characterization and Assessment in a Rat Model of Cocaine Dependence

Raveendra-Panickar Dhanya, Douglas J. Sheffler, Russell Dahl et al. · Journal of Medicinal Chemistry · 2014 · 39 citations · Full text

Pharmacological Characterization, Synaptic Transmission, Neurotransmitter +20