Carl Coolen

A selective ATP-competitive sphingosine kinase inhibitor demonstrates anti-cancer properties

Melissa R. Pitman, Jason A. Powell, Carl Coolen et al. · Oncotarget · 2015 · 74 citations · Full text

Sphingosine and FTY720 directly bind pro-survival 14-3-3 proteins to regulate their function

Joanna M. Woodcock, Yuefang Ma, Carl Coolen et al. · Cellular Signalling · 2010 · 73 citations

Protein Function, Signal Transduction, Signaling Pathway +11

Role of salt bridges in the dimer interface of 14-3-3ζ in dimer dynamics, N-terminal α-helical order, and molecular chaperone activity

Joanna M. Woodcock, Katy L. Goodwin, Jarrod J. Sandow et al. · Journal of Biological Chemistry · 2017 · 39 citations · Full text

Molecular Biology, Salt Bridges, Conformational Study +4

Destabilisation of dimeric 14-3-3 proteins as a novel approach to anti-cancer therapeutics

Joanna M. Woodcock, Carl Coolen, Katy L. Goodwin et al. · Oncotarget · 2015 · 38 citations · Full text

Protein Assembly, Apoptosis, Novel Approach +27

Human immunodeficiency virus 1 (HIV-1) virion infectivity factor (Vif) is part of reverse transcription complexes and acts as an accessory factor for reverse transcription

Jillian M. Carr, Carl Coolen, Adam Davis et al. · Virology · 2007 · 24 citations

Viral Replication, Reverse Transcription Complexes, Molecular Virology +13