Hervé Leh - Concepedia

Author

Hervé Leh

Centre National de la Recherche Scientifique ORCID

Also Known As

H Leh, H. LEH, H. Leh, Herve Leh, Hervé Leh, Hervé Leh, Hervé Leh (29723), Leh Herve, Leh Hervé, Leh, Hervé

Publications

2.5K

Citations

H-Index

Concepts

All Affiliations

Centre National de la Recherche Scientifique École Normale Supérieure Paris-Saclay Laboratoire de Biologie et Pharmacologie Appliquée Inserm Institut Gustave Roussy

About

Hervé Leh is an author at Centre National de la Recherche Scientifique specializing in medicine, natural sciences, and hiv.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	16	17	893
2	Natural Sciences	11	11	523
3	Biochemistry	8	8	474
4	Engineering	5	5	163
5	Biology	1	1	64

Hervé Leh

Publications

2.4K

Citations

H-Index

Page 1

	Year	Citations
Styrylquinoline Derivatives: A New Class of Potent HIV-1 Integrase Inhibitors That Block HIV-1 Replication in CEM Cells Khalid Mekouar, Jean‐François Mouscadet, Didier Desmaële, Journal of Medicinal Chemistry	1998	223
Structure−Activity Relationships and Binding Mode of Styrylquinolines as Potent Inhibitors of HIV-1 Integrase and Replication of HIV-1 in Cell Culture Fatima Zouhiri, Jean‐François Mouscadet, Khalid Mekouar, Journal of Medicinal Chemistry Hiv-1 InMedicinal ChemistryHiv-1 IntegraseBiochemistryMedicine	2000	148
Oligomeric States of the HIV-1 Integrase As Measured by Time-Resolved Fluorescence Anisotropy Eric Deprez, Patrick Tauc, Hervé Leh, Biochemistry	2000	133
Determinants of Mg<sup>2+</sup>-Dependent Activities of Recombinant Human Immunodeficiency Virus Type 1 Integrase Hervé Leh, Priscille Brodin, Julien Bischerour, Biochemistry	2000	125
Linker-modified quinoline derivatives targeting HIV-1 integrase: synthesis and biological activity Christophe Bénard, Fatima Zouhiri, Marie Normand‐Bayle, Bioorganic & Medicinal Chemistry Letters Medicinal ChemistryMedicineImmunologyLinker-modified Quinoline DerivativesAntiviral Drug Development	2004	92
DNA binding induces dissociation of the multimeric form of HIV-1 integrase: A time-resolved fluorescence anisotropy study Eric Deprez, Patrick Tauc, Hervé Leh, Proceedings of the National Academy of Sciences	2001	88
Peptide Inhibitors of HIV-1 Integrase Dissociate the Enzyme Oligomers Richard G. Maroun, Stéphanie Gayet, Mohamed Salah Benleulmi, Biochemistry	2001	83
Styrylquinolines, Integrase Inhibitors Acting Prior to Integration: a New Mechanism of Action for Anti-Integrase Agents Sabine Bonnenfant, Claire M. Thomas, Claudio Vita, Journal of Virology Virus EntryImmunologyIntegrase GeneAntiviral DrugPharmaceutical Chemistry	2004	78
HIV-1 replication inhibitors of the styrylquinoline class: introduction of an additional carboxyl group at the C-5 position of the quinoline Fatima Zouhiri, Michèle Danet, Christophe Bénard, Tetrahedron Letters Medicinal ChemistryBiochemistryC-5 PositionNatural SciencesHiv-1 Replication Inhibitors	2005	75
Characterization of the Nuclear Import Pathway for HIV-1 Integrase Christel Depienne, Aurélie Mousnier, Hervé Leh, Journal of Biological Chemistry	2001	75

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