Oxygen environment and islet size are the primary limiting factors of isolated pancreatic islet survival

Hirotake Komatsu, Colin A. Cook, Chia-Hao Wang, +5

PLoS ONE

CD5 expression is potentially predictive of poor outcome among biomarkers in patients with diffuse large B-cell lymphoma receiving rituximab plus CHOP therapy

Daisuke Ennishi, Kengo Takeuchi, Masaru Yokoyama, +10

Annals of Oncology

Hematological MalignancyLymphoid NeoplasiaAutoimmune DiseaseChop TherapyPoor Outcome +9

GNASR201H and KrasG12D cooperate to promote murine pancreatic tumorigenesis recapitulating human intraductal papillary mucinous neoplasm

Katsunobu Taki, Masaki Ohmuraya, Etsuko Tanji, +7

Oncogene

Pancreatic CancerMedicinePathologyCancer GeneticsCancer Biology +4

A GNAS Mutation Found in Pancreatic Intraductal Papillary Mucinous Neoplasms Induces Drastic Alterations of Gene Expression Profiles with Upregulation of Mucin Genes

Hirotake Komatsu, Etsuko Tanji, Naoaki Sakata, +7

PLoS ONE

GeneticsPathologyMolecular GeneticsGene Expression ProfilesCancer Biology +22

Soluble interleukin-2 receptor retains prognostic value in patients with diffuse large B-cell lymphoma receiving rituximab plus CHOP (RCHOP) therapy

Daisuke Ennishi, Masaru Yokoyama, Y. Terui, +9

Annals of Oncology

Hematological MalignancyLymphoid NeoplasiaMedicinePrognostic ValueImmunology +7

Posttransplant oxygen inhalation improves the outcome of subcutaneous islet transplantation: A promising clinical alternative to the conventional intrahepatic site

Hirotake Komatsu, Jeffrey Rawson, Alyssa Barriga, +6

American Journal of Transplantation

Subcutaneous TissueSolid Organ TransplantationTissue TransplantationSurgeryPancreas Transplantation +18

Isolated human islets require hyperoxia to maintain islet mass, metabolism, and function

Hirotake Komatsu, Dongyang Kang, Leonard Medrano, +7

Biochemical and Biophysical Research Communications

Insulin SignalingPhysiologyDiabetesMetabolic RegulationMetabolic State +8

Clinicopathological features and surgical outcomes of adenosquamous carcinoma of the pancreas: a retrospective analysis of patients with resectable stage tumors

Hirotake Komatsu, Shinichi Egawa, Fuyuhiko Motoi, +6

Surgery Today

Pancoast SyndromeSurgical OncologyPancreatic CancerPancreatic Fluid CollectionMedicine +9

Semi-Automated Assessment of Human Islet Viability Predicts Transplantation Outcomes in a Diabetic Mouse Model

Mayra Salgado, Nelson Gonzalez, Leonard Medrano, +7

Cell Transplantation

Optimizing Temperature and Oxygen Supports Long-term Culture of Human Islets

Hirotake Komatsu, Jeffrey Rawson, Leonard Medrano, +8

Transplantation