Ferroptosis of tumour neutrophils causes immune suppression in cancer

Rina Kim, Ayumi Hashimoto, Nune Markosyan, +20

Nature

Cancer ImmunosurveillanceGranulocyteImmunologyTumor ImmunityPathology +5

tRF/miR-1280 Suppresses Stem Cell–like Cells and Metastasis in Colorectal Cancer

Bingqing Huang, Huipeng Yang, Xixi Cheng, +16

Cancer Research

Transitory presence of myeloid-derived suppressor cells in neonates is critical for control of inflammation

Yumei He, Xing Li, Michela Perego, +11

Nature Medicine

InflammationCytokineAutoimmune DiseaseAllergyImmunology +8

Unique pattern of neutrophil migration and function during tumor progression

Sima Patel, Shuyu Fu, Jérôme Mastio, +19

Nature Immunology

Unique PatternGranulocyteCell TraffickingImmunologyBlood Cell +7

Identification of monocyte-like precursors of granulocytes in cancer as a mechanism for accumulation of PMN-MDSCs

Jérôme Mastio, Thomas Condamine, George A. Dominguez, +22

The Journal of Experimental Medicine

Immune suppressive activity of myeloid-derived suppressor cells in cancer requires inactivation of the type I interferon pathway

Kevin Alicea-Torres, Emilio Sanseviero, Jun Gui, +17

Nature Communications

Lactoferrin-induced myeloid-derived suppressor cell therapy attenuates pathologic inflammatory conditions in newborn mice

Yufeng Liu, Michela Perego, Qiang Xiao, +16

Journal of Clinical Investigation

Lung InflammationImmunologyImmune RegulationCell DeathImmune System +17

A Novel Selective Inhibitor JBI-589 Targets PAD4-Mediated Neutrophil Migration to Suppress Tumor Progression

Hui Deng, Cindy Lin, Laura Garcia-Gerique, +15

Cancer Research

Embelin inhibits pancreatic cancer progression by directly inducing cancer cell apoptosis and indirectly restricting IL-6 associated inflammatory and immune suppressive cells11These authors contributed equally to this work.

Meiyu Peng, Bingqing Huang, Qi Zhang, +13

Cancer Letters

Tumor BiologyCancer Cell ApoptosisCancer ImmunosurveillancePancreatic CancerMedicine +8

Apolipoprotein A-I mimetic peptide 4F suppresses tumor-associated macrophages and pancreatic cancer progression

Meiyu Peng, Qi Zhang, Yingnan Cheng, +12

Oncotarget