4‐Acyl Pyrroles: Mimicking Acetylated Lysines in Histone Code Reading

Xavier Lucas, Daniel Wohlwend, Martin Hügle, +5

Angewandte Chemie International Edition

ChromatinBiochemistryLeukemia Cell LinesMedicineHistone Code Reading +13

Homologous bd oxidases share the same architecture but differ in mechanism

Alexander Theßeling, Tim Rasmussen, Sabrina Burschel, +5

Nature Communications

Assembly of methylated KDM1A and CHD1 drives androgen receptor–dependent transcription and translocation

Eric Metzger, Dominica Willmann, Joel McMillan, +20

Nature Structural & Molecular Biology

ChromatinTranscriptional RegulationSignal TransductionMedicineNatural Sciences +10

Substrate recognition and mechanism revealed by ligand-bound polyphosphate kinase 2 structures

Alice E. Parnell, Silja Mordhorst, F. Kemper, +11

Proceedings of the National Academy of Sciences

Crystal structure analysis of a fatty acid double-bond hydratase from<i>Lactobacillus acidophilus</i>

Anton Volkov, Sohail Khoshnevis, Piotr Neumann, +3

Acta Crystallographica Section D Biological Crystallography

Crystal StructureCrystal Structure AnalysisBiochemistryNatural SciencesProtein X-ray Crystallography +9

4-Acyl Pyrrole Derivatives Yield Novel Vectors for Designing Inhibitors of the Acetyl-Lysine Recognition Site of BRD4(1)

Martin Hügle, Xavier Lucas, Gerhard Weitzel, +6

Journal of Medicinal Chemistry

Combinatorial ChemistryDrug TargetMolecular BiologyBet ProteinsChemical Biology +19

Structure of Escherichia coli cytochrome bd-II type oxidase with bound aurachin D

Antonia Grauel, Jan Kägi, Tim Rasmussen, +10

Nature Communications

A mechanism to prevent production of reactive oxygen species by Escherichia coli respiratory complex I

Marius Schulte, Klaudia Frick, Emmanuel Gnandt, +9

Nature Communications

Structural Basis for RanGTP Independent Entry of Spliceosomal U snRNPs into the Nucleus

Daniel Wohlwend, Anja Strasser, Achim Dickmanns, +1

Journal of Molecular Biology

ChromatinRangtp Independent EntryGeneticsGene StructureMolecular Biology +7

Beyond the BET Family: Targeting CBP/p300 with 4‐Acyl Pyrroles

Martin Hügle, Xavier Lucas, Dmytro Ostrovskyi, +8

Angewandte Chemie International Edition

Drug TargetChemoprevention StrategyPharmacotherapyCancer BiologyPharmaceutical Chemistry +19