All-trans retinoic acid is a ligand for the orphan nuclear receptor RORβ

C. Stehlin-Gaon, Dominica Willmann, Denis Zeyer, +5

Nature Structural & Molecular Biology

Molecular PharmacologySignal TransductionCell RegulationReceptor (Biochemistry)Molecular Biology +4

Selective targeting of the BRG/PB1 bromodomains impairs embryonic and trophoblast stem cell maintenance

Oleg Fedorov, Josefina Castex, C. Tallant, +20

Science Advances

Impairment of prostate cancer cell growth by a selective and reversible lysine‐specific demethylase 1 inhibitor

Dominica Willmann, Soyoung Lim, Stefan Wetzel, +11

International Journal of Cancer

Histone ModificationsAndrogen ReceptorEpigenetic ChangeEpigeneticsTumor Biology +17

LSD1 promotes oxidative metabolism of white adipose tissue

Delphine Duteil, Eric Metzger, Dominica Willmann, +8

Nature Communications

Metabolic SyndromeBiochemistryPhysiologyMetabolic RegulationWhite Adipose Tissue +5

KDM4 Inhibition Targets Breast Cancer Stem–like Cells

Eric Metzger, Stella S. Stepputtis, Juliane Strietz, +17

Cancer Research

KMT9 monomethylates histone H4 lysine 12 and controls proliferation of prostate cancer cells

Eric Metzger, Sheng Wang, Sylvia Urban, +18

Nature Structural & Molecular Biology

Cancer ResearchChromatinChromatin RemodelingMedicineControls Proliferation +9

Lsd1 Ablation Triggers Metabolic Reprogramming of Brown Adipose Tissue

Delphine Duteil, Milica Tošić, Franziska Lausecker, +15

Cell Reports

ObesityMetabolic SyndromeAdipose TissuePhysiologyBrown Adipose Tissue +11

Assembly of methylated KDM1A and CHD1 drives androgen receptor–dependent transcription and translocation

Eric Metzger, Dominica Willmann, Joel McMillan, +20

Nature Structural & Molecular Biology

ChromatinTranscriptional RegulationSignal TransductionMedicineNatural Sciences +10

Lsd1 regulates skeletal muscle regeneration and directs the fate of satellite cells

Milica Tošić, Anita L. Allen, Dominica Willmann, +4

Nature Communications

Nonpeptidic Propargylamines as Inhibitors of Lysine Specific Demethylase 1 (LSD1) with Cellular Activity

Martin Schmitt, Alexander‐Thomas Hauser, Luca Carlino, +9

Journal of Medicinal Chemistry

Drug TargetPharmacotherapyChemical BiologyCellular ActivityLysine Demethylases +15