Mingfu Tian

SARS-CoV-2 N protein promotes NLRP3 inflammasome activation to induce hyperinflammation

Pan Pan, Miaomiao Shen, Zhenyang Yu et al. · Nature Communications · 2021 · 489 citations · Full text

HIF-1α promotes SARS-CoV-2 infection and aggravates inflammatory responses to COVID-19

Mingfu Tian, Weiyong Liu, Xiang Li et al. · Signal Transduction and Targeted Therapy · 2021 · 246 citations · Full text

STING promotes NLRP3 localization in ER and facilitates NLRP3 deubiquitination to activate the inflammasome upon HSV-1 infection

Wenbiao Wang, Dingwen Hu, Caifeng Wu et al. · PLoS Pathogens · 2020 · 221 citations · Full text

Innate Immune System, Viral Pathogenesis, Immunology +24

Zika virus infection induces host inflammatory responses by facilitating NLRP3 inflammasome assembly and interleukin-1β secretion

Wenbiao Wang, Geng Li, De Wu et al. · Nature Communications · 2018 · 212 citations · Full text

SARS-CoV-2 Nucleocapsid Protein Interacts with RIG-I and Represses RIG-Mediated IFN-β Production

Keli Chen, Feng Xiao, Dingwen Hu et al. · Viruses · 2020 · 166 citations · Full text

Viral Replication, N Protein, Viral Pathogenesis +18