Keli Chen

SARS-CoV-2 N protein promotes NLRP3 inflammasome activation to induce hyperinflammation

Pan Pan, Miaomiao Shen, Zhenyang Yu et al. · Nature Communications · 2021 · 489 citations · Full text

CD36 inhibits β-catenin/c-myc-mediated glycolysis through ubiquitination of GPC4 to repress colorectal tumorigenesis

Yuan Fang, Zhiyong Shen, Yizhi Zhan et al. · Nature Communications · 2019 · 242 citations · Full text

A novel lncRNA uc.134 represses hepatocellular carcinoma progression by inhibiting CUL4A-mediated ubiquitination of LATS1

Wen Ni, Yuqin Zhang, Zetao Zhan et al. · Journal of Hematology & Oncology · 2017 · 228 citations · Full text

STING promotes NLRP3 localization in ER and facilitates NLRP3 deubiquitination to activate the inflammasome upon HSV-1 infection

Wenbiao Wang, Dingwen Hu, Caifeng Wu et al. · PLoS Pathogens · 2020 · 221 citations · Full text

Innate Immune System, Viral Pathogenesis, Immunology +24

SARS-CoV-2 Nucleocapsid Protein Interacts with RIG-I and Represses RIG-Mediated IFN-β Production

Keli Chen, Feng Xiao, Dingwen Hu et al. · Viruses · 2020 · 166 citations · Full text

Viral Replication, N Protein, Viral Pathogenesis +18