Fumiaki Sato

PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy

Noriyuki Matsuda, Shigeto Sato, Kahori Shiba et al. · The Journal of Cell Biology · 2010 · 1.9K citations · Full text

Mitophagy, Cell Death, Molecular Biology +16

Neratinib after trastuzumab-based adjuvant therapy in HER2-positive breast cancer (ExteNET): 5-year analysis of a randomised, double-blind, placebo-controlled, phase 3 trial

Miguel Martín, Frankie A. Holmes, Bent Ejlertsen et al. · The Lancet Oncology · 2017 · 578 citations

5-Year Analysis, Breast Oncology, Oncology +10

Caffeine induces apoptosis by enhancement of autophagy via PI3K/Akt/mTOR/p70S6K inhibition

Shinji Saiki, Yukiko Sasazawa, Yoko Imamichi et al. · Autophagy · 2011 · 417 citations · Full text

Cell Autophagy, Mitophagy, Signal Transduction +15

Pharmacologic unmasking of epigenetically silenced tumor suppressor genes in esophageal squamous cell carcinoma

Keishi Yamashita, Sunil Upadhyay, Motonobu Osada et al. · Cancer Cell · 2002 · 342 citations · Full text

Tumor Biology, Esophageal Cancer, Medicine +7

The miR-106b-25 Polycistron, Activated by Genomic Amplification, Functions as an Oncogene by Suppressing p21 and Bim

Takatsugu Kan, Fumiaki Sato, Tetsuo Ito et al. · Gastroenterology · 2009 · 265 citations · Full text

Genomic Amplification, Genetics, Mir-106b-25 Polycistron +9