Concepedia

Elizabeth R. Sprague

ER

13

Publications

1.3K

Citations

12

H-Index

2000

Active since

Affiliations

Novartis (United States)(Current)

Howard Hughes Medical Institute

Novartis (Switzerland)

Novartis Institutes for BioMedical Research

California Institute of Technology

Elizabeth R. Sprague is an author at Novartis (United States) specializing in medicine, cell biology, and molecular biology.

Top concepts

MedicineCell BiologyMolecular BiologyNatural SciencesImmunologyTumor BiologyCell SignalingDrug DiscoveryCancer ResearchGene Expression

Publications per year

2000–2021

13

Publications

13

Disordered methionine metabolism in MTAP/CDKN2A-deleted cancers leads to dependence on PRMT5

Konstantinos J. Mavrakis, E. Robert McDonald, Michael R. Schlabach et al. · Science · 2016 · 538 citations

Crystal Structure of the HSV-1 Fc Receptor Bound to Fc Reveals a Mechanism for Antibody Bipolar Bridging

Elizabeth R. Sprague, Chu Wang, David Baker et al. · PLoS Biology · 2006 · 136 citations · Full text

Structure of the C-terminal domain of Tup1, a corepressor of transcription in yeast

Elizabeth R. Sprague · The EMBO Journal · 2000 · 131 citations · Full text

Transcriptional Regulation, Natural Sciences, Gene Structure +7

An Antibody That Locks HER3 in the Inactive Conformation Inhibits Tumor Growth Driven by HER2 or Neuregulin

Andrew P. Garner, Carl Uli Bialucha, Elizabeth R. Sprague et al. · Cancer Research · 2013 · 121 citations · Full text

Her2/her3 Dimerization, Medicine, Inactive Conformation +12

Mechanisms Decreasing <i>In Vitro</i> Susceptibility to the LpxC Inhibitor CHIR-090 in the Gram-Negative Pathogen Pseudomonas aeruginosa

Ruth E. Caughlan, Adriana K. Jones, Angela M. DeLucia et al. · Antimicrobial Agents and Chemotherapy · 2011 · 57 citations · Full text

Microbial Pathogens, Molecular Regulation, Molecular Biology +28

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