A mutation in the insulin 2 gene induces diabetes with severe pancreatic β-cell dysfunction in the Mody mouse

Jie Wang, Toshiyuki Takeuchi, Shigeyasu Tanaka, +6

Journal of Clinical Investigation

Autophagy requires endoplasmic reticulum targeting of the PI3-kinase complex via Atg14L

Kohichi Matsunaga, Eiji Morita, Tatsuya Saitoh, +5

The Journal of Cell Biology

Autophagy ComplexMitophagyCell AutophagySignal TransductionSignaling Pathway +11

Elimination of cdc2 phosphorylation sites in the cdc25 phosphatase blocks initiation of M-phase.

Tetsuro Izumi, James L. Maller

Molecular Biology of the Cell

Cdc2 Phosphorylation SitesSignal TransductionCell RegulationCell DivisionMolecular Pathway +13

Periodic changes in phosphorylation of the Xenopus cdc25 phosphatase regulate its activity.

Tetsuro Izumi, D H Walker, James L. Maller

Molecular Biology of the Cell

Cdc25 Tyrosine PhosphataseTyrosine 15Molecular RegulationMolecular BiologyCytoskeleton +18

Modular Genetic Control of Sexually Dimorphic Behaviors

Xiaohong Xu, Jennifer Coats, Cindy F. Yang, +5

Cell

Sex DeterminationMedicineGeneticsEvolutionary BiologySexual Behavior +4

Induction of metaphase arrest in cleaving Xenopus embryos by MAP kinase

Olivier Haccard, Boris Šarčević, Andrea L. Lewellyn, +5

Science

The Rab27a/Granuphilin Complex Regulates the Exocytosis of Insulin-Containing Dense-Core Granules

Zhaohong Yi, Hiromi Yokota, Seiji Torii, +6

Molecular and Cellular Biology

Dominant Negative Pathogenesis by Mutant Proinsulin in the Akita Diabetic Mouse

Tetsuro Izumi, Hiromi Yokota‐Hashimoto, Shengli Zhao, +3

Diabetes

Tyrosine phosphorylation of common and specific sets of cellular proteins rapidly induced by insulin, insulin-like growth factor I, and epidermal growth factor in an intact cell.

Takashi Kadowaki, Shigeo Koyasu, Eisuke Nishida, +6

Journal of Biological Chemistry

In vivo gene delivery by cationic tetraamino fullerene

Rui Maeda-Mamiya, Eisei Noiri, Hiroyuki Isobe, +7

Proceedings of the National Academy of Sciences

Cell-based Drug DeliveryNanomedicineEngineeringEgfp Gene ExpressionWater-soluble Fullerenes +7