Irene H. Cheng

Reducing Endogenous Tau Ameliorates Amyloid ß-Induced Deficits in an Alzheimer's Disease Mouse Model

Erik D. Roberson, Kimberly Scearce‐Levie, Jorge J. Palop et al. · Science · 2007 · 1.9K citations

Accelerating Amyloid-β Fibrillization Reduces Oligomer Levels and Functional Deficits in Alzheimer Disease Mouse Models

Irene H. Cheng, Kimberly Scearce‐Levie, Justin Legleiter et al. · Journal of Biological Chemistry · 2007 · 406 citations · Full text

Neurodegenerative Diseases, Arctic Mutation, Alzheimer's Disease +13

Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease

Rene O. Sanchez-Mejia, John W. Newman, Sandy Toh et al. · Nature Neuroscience · 2008 · 366 citations · Full text

Alzheimer's Disease, Molecular Neuroscience, Medicine +12

Full-length TDP-43 forms toxic amyloid oligomers that are present in frontotemporal lobar dementia-TDP patients

Yu-Sheng Fang, Kuen‐Jer Tsai, Yu-Jen Chang et al. · Nature Communications · 2014 · 198 citations · Full text

Amyloid Oligomers, Neurodegenerative Diseases, Alzheimer's Disease +10

Distinct Effects of Zn2+, Cu2+, Fe3+, and Al3+ on Amyloid-β Stability, Oligomerization, and Aggregation

Wei-Ting Chen, Yi-Hung Liao, Hui-Ming Yu et al. · Journal of Biological Chemistry · 2011 · 195 citations · Full text