Latifa Chachi

Effect of tralokinumab, an interleukin-13 neutralising monoclonal antibody, on eosinophilic airway inflammation in uncontrolled moderate-to-severe asthma (MESOS): a multicentre, double-blind, randomised, placebo-controlled phase 2 trial

Richard Russell, Latifa Chachi, J. Mark FitzGerald et al. · The Lancet Respiratory Medicine · 2018 · 130 citations · Full text

Inflammation, Asthma, Placebo-controlled Phase 2 +10

DP ₂ antagonism reduces airway smooth muscle mass in asthma by decreasing eosinophilia and myofibroblast recruitment

Ruth Saunders, Himanshu Kaul, Rachid Berair et al. · Science Translational Medicine · 2019 · 76 citations · Full text

<i>In vitro</i>,<i>in silico</i>and<i>in vivo</i>study challenges the impact of bronchial thermoplasty on acute airway smooth muscle mass loss

Igor L. Chernyavsky, Richard Russell, Ruth Saunders et al. · European Respiratory Journal · 2018 · 65 citations · Full text

NADPH Oxidase-4 Overexpression Is Associated With Epithelial Ciliary Dysfunction in Neutrophilic Asthma

Wing-Yan Heidi Wan, Fay Hollins, Louise Haste et al. · CHEST Journal · 2016 · 53 citations · Full text

Inflammation, Asthma, Epithelial Ciliary Dysfunction +9

Functional KCa3.1 Channels Regulate Steroid Insensitivity in Bronchial Smooth Muscle Cells

Latifa Chachi, Aarti Shikotra, S. Mark Duffy et al. · The Journal of Immunology · 2013 · 37 citations · Full text