The combination of thymoquinone and paclitaxel shows anti-tumor activity through the interplay with apoptosis network in triple-negative breast cancer

Çağrı Şakalar, Kenan İzgi, Banu İskender, +6

Tumor Biology

Connective tissue and its growth factor CTGF distinguish the morphometric and molecular remodeling of the bladder in a model of neurogenic bladder

Cengiz Z. Altuntas, Firouz Daneshgari, Kenan İzgi, +5

American Journal of Physiology-Renal Physiology

ImmunodeficienciesImmunologyImmune RegulationPathologyCd4 T Cell Responses +26

Chronic pelvic allodynia is mediated by CCL2 through mast cells in an experimental autoimmune cystitis model

Fuat Bicer, Cengiz Z. Altuntas, Kenan İzgi, +4

American Journal of Physiology-Renal Physiology

InflammationCytokineAllergyAutoimmune DiseaseMedicine +11

Novel anti-cancer agent myrtucommulone-A and thymoquinone abrogate epithelial–mesenchymal transition in cancer cells mainly through the inhibition of PI3K/AKT signalling axis

Banu İskender, Kenan İzgi, Halit Canatan

Molecular and Cellular Biochemistry

Tumor BiologyOncologyOncogenic AgentMedicineTumor Immunity +10

Uroplakin Peptide-Specific Autoimmunity Initiates Interstitial Cystitis/Painful Bladder Syndrome in Mice

Kenan İzgi, Cengiz Z. Altuntas, Fuat Bicer, +5

PLoS ONE

Myrtucommulone-A Induces both Extrinsic and Intrinsic Apoptotic Pathways in Cancer Cells

Kenan İzgi, Banu İskender, Johann Jauch, +4

Journal of Biochemical and Molecular Toxicology

ApoptosisImmunologyCell DeathCancer BiologyCell Death Mechanisms +14

Inhibition of epithelial-mesenchymal transition in bladder cancer cells via modulation of mTOR signalling

Banu İskender, Kenan İzgi, Esra Hizar, +4

Tumor Biology

Advanced glycation end products facilitate bacterial adherence in urinary tract infection in diabetic mice

Ahmet Özer, Cengiz Z. Altuntas, Kenan İzgi, +4

Pathogens and Disease

Type 1UrologyBacterial AdherenceBiochemistryUrinary Tract Infection +11

Mesenchymal stem cell therapy in a rat model of birth-trauma injury: functional improvements and biodistribution

Zhina Sadeghi, Justin P Isariyawongse, Michael Kavran, +7

International Urogynecology Journal

Tissue EngineeringRegenerative MedicineEngineeringMedicineAdult Stem Cell +13

Impaired cytokine expression, neutrophil infiltration and bacterial clearance in response to urinary tract infection in diabetic mice

Ahmet Özer, Cengiz Z. Altuntas, Fuat Bicer, +4

Pathogens and Disease