Rosie Upton

Hybrid mass spectrometry methods reveal lot-to-lot differences and delineate the effects of glycosylation on the tertiary structure of Herceptin®

Rosie Upton, Lukasz G. Migas, Kamila J. Pacholarz et al. · Chemical Science · 2019 · 33 citations · Full text

Orthogonal Assessment of Biotherapeutic Glycosylation: A Case Study Correlating N-Glycan Core Afucosylation of Herceptin with Mechanism of Action

Rosie Upton, Leonard N. Bell, Colin P. Guy et al. · Analytical Chemistry · 2016 · 26 citations · Full text

Bioorganic Chemistry, Glycobiology, Immunology +18

Cold Denaturation of Proteins in the Absence of Solvent: Implications for Protein Storage**

Emma Norgate, Rosie Upton, Kjetil Hansen et al. · Angewandte Chemie International Edition · 2022 · 21 citations · Full text

Protein Chemistry, Cold Denaturation, Vt Im-ms +12

Protein Unfolding in Freeze Frames: Intermediate States are Revealed by Variable-Temperature Ion Mobility–Mass Spectrometry

Jakub Ujma, Jacquelyn R. Jhingree, Emma Norgate et al. · Analytical Chemistry · 2022 · 12 citations · Full text