Frank Pui-Ling Lai

Identification of Genes Associated With Hirschsprung Disease, Based on Whole-Genome Sequence Analysis, and Potential Effects on Enteric Nervous System Development

Clara Sze-Man Tang, Peng Li, Frank Pui-Ling Lai et al. · Gastroenterology · 2018 · 80 citations

Bioinformatics, Whole-genome Sequence Analysis, Developmental Biology +12

Correction of Hirschsprung-Associated Mutations in Human Induced Pluripotent Stem Cells Via Clustered Regularly Interspaced Short Palindromic Repeats/Cas9, Restores Neural Crest Cell Function

Frank Pui-Ling Lai, Sin-Ting Lau, John Wong et al. · Gastroenterology · 2017 · 78 citations · Full text

Hirschsprung-associated Mutations, Induced Pluripotent Stem Cell, Developmental Biology +9

Identification of GLI Mutations in Patients With Hirschsprung Disease That Disrupt Enteric Nervous System Development in Mice

Jessica Aijia Liu, Frank Pui-Ling Lai, Hongsheng Gui et al. · Gastroenterology · 2015 · 43 citations · Full text

Knockout Mouse, Developmental Biology, Mendelian Disorder +8

Activation of Hedgehog Signaling Promotes Development of Mouse and Human Enteric Neural Crest Cells, Based on Single-Cell Transcriptome Analyses

Sin-Ting Lau, Zhixin Li, Frank Pui-Ling Lai et al. · Gastroenterology · 2019 · 43 citations · Full text

Cell Lineage, Developmental Biology, Single-cell Transcriptome Analyses +6

Transcriptomics of Hirschsprung disease patient-derived enteric neural crest cells reveals a role for oxidative phosphorylation

Zhixin Li, Kathy Nga-Chu Lui, Sin-Ting Lau et al. · Nature Communications · 2023 · 20 citations · Full text