Frank Pui-Ling Lai

Identification of Genes Associated With Hirschsprung Disease, Based on Whole-Genome Sequence Analysis, and Potential Effects on Enteric Nervous System Development

Clara Sze-Man Tang, Peng Li, Frank Pui-Ling Lai et al. · Gastroenterology · 2018 · 82 citations

Life Sciences, Genetics, Molecular Genetics +17

Correction of Hirschsprung-Associated Mutations in Human Induced Pluripotent Stem Cells Via Clustered Regularly Interspaced Short Palindromic Repeats/Cas9, Restores Neural Crest Cell Function

Frank Pui-Ling Lai, Sin-Ting Lau, John Wong et al. · Gastroenterology · 2017 · 78 citations · Full text

Life Sciences, Genetics, Molecular Genetics +14

Identification of GLI Mutations in Patients With Hirschsprung Disease That Disrupt Enteric Nervous System Development in Mice

Jessica Aijia Liu, Frank Pui-Ling Lai, Hongsheng Gui et al. · Gastroenterology · 2015 · 44 citations · Full text

Life Sciences, Genetics, Molecular Genetics +12

Activation of Hedgehog Signaling Promotes Development of Mouse and Human Enteric Neural Crest Cells, Based on Single-Cell Transcriptome Analyses

Sin-Ting Lau, Zhixin Li, Frank Pui-Ling Lai et al. · Gastroenterology · 2019 · 43 citations · Full text

Life Sciences, Cell Biology, Developmental Biology +16

Divergent lineage trajectories and genetic landscapes in human gastric intestinal metaplasia organoids associated with early neoplastic progression

Sarah S K Yue, Yin Tong, Hoi Cheong Siu et al. · Gut · 2024 · 29 citations · Full text

Medicine, Cell Biology, Oncology +17