Sin-Ting Lau

Identification of Genes Associated With Hirschsprung Disease, Based on Whole-Genome Sequence Analysis, and Potential Effects on Enteric Nervous System Development

Clara Sze-Man Tang, Peng Li, Frank Pui-Ling Lai et al. · Gastroenterology · 2018 · 80 citations

Bioinformatics, Whole-genome Sequence Analysis, Developmental Biology +12

Correction of Hirschsprung-Associated Mutations in Human Induced Pluripotent Stem Cells Via Clustered Regularly Interspaced Short Palindromic Repeats/Cas9, Restores Neural Crest Cell Function

Frank Pui-Ling Lai, Sin-Ting Lau, John Wong et al. · Gastroenterology · 2017 · 78 citations · Full text

Hirschsprung-associated Mutations, Induced Pluripotent Stem Cell, Developmental Biology +9

Hedgehog/Notch-induced premature gliogenesis represents a new disease mechanism for Hirschsprung disease in mice and humans

María-Mercé García-Barceló, Benjamin Hon Kei Yip, Hiu-Ching Poon et al. · Journal of Clinical Investigation · 2011 · 75 citations · Full text

Pathology, Disease Gene Identification, Hscr Susceptibility Genes +18

Activation of Hedgehog Signaling Promotes Development of Mouse and Human Enteric Neural Crest Cells, Based on Single-Cell Transcriptome Analyses

Sin-Ting Lau, Zhixin Li, Frank Pui-Ling Lai et al. · Gastroenterology · 2019 · 43 citations · Full text

Cell Lineage, Developmental Biology, Single-cell Transcriptome Analyses +6

Transcriptomics of Hirschsprung disease patient-derived enteric neural crest cells reveals a role for oxidative phosphorylation

Zhixin Li, Kathy Nga-Chu Lui, Sin-Ting Lau et al. · Nature Communications · 2023 · 20 citations · Full text