Luz-Elena Núñez

Identification of Mithramycin Analogues with Improved Targeting of the EWS-FLI1 Transcription Factor

Christy Osgood, Nichole Maloney, Christopher G. Kidd et al. · Clinical Cancer Research · 2016 · 71 citations · Full text

Modulation of the Activity of Sp Transcription Factors by Mithramycin Analogues as a New Strategy for Treatment of Metastatic Prostate Cancer

Anastasia Malek, Luz-Elena Núñez, Marco Magistri et al. · PLoS ONE · 2012 · 59 citations · Full text

Inhibition of SP1 by the mithramycin analog EC-8042 efficiently targets tumor initiating cells in sarcoma

Juan Tornín, Lucia Martínez-Cruzado, Laura Santos et al. · Oncotarget · 2016 · 49 citations · Full text

Mithramycin A and Mithralog EC-8042 Inhibit SETDB1 Expression and Its Oncogenic Activity in Malignant Melanoma

Aniello Federico, Tamara Steinfass, Lionel Larribère et al. · Molecular Therapy — Oncolytics · 2020 · 47 citations · Full text

The activity of a novel mithramycin analog is related to its binding to DNA, cellular accumulation, and inhibition of Sp1-driven gene transcription

Azahara Fernández-Guizán, Sylvia Mansilla, Francisca Barceló et al. · Chemico-Biological Interactions · 2014 · 40 citations · Full text

Novel Mithramycin Analog, Cellular Accumulation, Engineering +9