Suzanne E. Holmes

Triterpenoid saponin augmention of saporin-based immunotoxin cytotoxicity for human leukaemia and lymphoma cells is partially immunospecific and target molecule dependent

Suzanne E. Holmes, Christopher Bachran, Hendrik Fuchs et al. · Immunopharmacology and Immunotoxicology · 2014 · 26 citations

Medicine, Immunology, Pharmacology +11

Membrane cholesterol is essential for triterpenoid saponin augmentation of a saporin-based immunotoxin directed against CD19 on human lymphoma cells

Wendy S. Smith, Ella J. Baker, Suzanne E. Holmes et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes · 2017 · 19 citations · Full text

Medicine, Cancer Biology, Immunology +10

A Flow Cytometric Method to Quantify the Endosomal Escape of a Protein Toxin to the Cytosol of Target Cells

Harrison J. Wensley, David A. Johnston, Wendy S. Smith et al. · Pharmaceutical Research · 2019 · 16 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13

The Role of Cholesterol on Triterpenoid Saponin-Induced Endolysosomal Escape of a Saporin-Based Immunotoxin

Wendy S. Smith, David A. Johnston, Harrison J. Wensley et al. · International Journal of Molecular Sciences · 2020 · 11 citations · Full text

Life Sciences, Biochemistry, Immunology +13