Whole genome sequencing of multiple <i>Leishmania donovani</i> clinical isolates provides insights into population structure and mechanisms of drug resistance

Tim Downing, Hideo Imamura, Saskia Decuypere, +17

Genome Research

Evolutionary genomics of epidemic visceral leishmaniasis in the Indian subcontinent

Hideo Imamura, Tim Downing, Frederik Van den Broeck, +30

eLife

GeneticsGenomicsVisceral LeishmaniasisParasite GenomicsDrug Resistance +16

Genomic Confirmation of Hybridisation and Recent Inbreeding in a Vector-Isolated Leishmania Population

Matthew B. Rogers, Tim Downing, Barbara A. Smith, +7

PLoS Genetics

Comparative GenomicsGeneticsRecent InbreedingGenomicsVisceral Leishmaniasis +19

Global genome diversity of the Leishmania donovani complex

Susanne U. Franssen, Caroline Durrant, Olivia Stark, +18

eLife

The avian Toll-Like receptor pathway—Subtle differences amidst general conformity

Paul Cormican, Andrew T. Lloyd, Tim Downing, +3

Developmental & Comparative Immunology

InflammationToll-like ReceptorsMolecular ImmunologyHost ResponsePathogenesis +8

Development and Evaluation of a Novel Loop-Mediated Isothermal Amplification Assay for Diagnosis of Cutaneous and Visceral Leishmaniasis

Emily R. Adams, Gerard J. Schoone, Inge Versteeg, +11

Journal of Clinical Microbiology

An Escherichia coli ST131 pangenome atlas reveals population structure and evolution across 4,071 isolates

Arun Decano, Tim Downing

Scientific Reports

<i>In vitro</i> selection of miltefosine resistance in promastigotes of <i>Leishmania donovani</i> from Nepal: genomic and metabolomic characterization

C. D. Shaw, Julien Lonchamp, Tim Downing, +11

Molecular Microbiology

The Differential Evolutionary Dynamics of Avian Cytokine and TLR Gene Classes

Tim Downing, Andrew T. Lloyd, Cliona O’Farrelly, +1

The Journal of Immunology

GeneticsImmunologyGenomicsImmune SystemDifferential Evolutionary Dynamics +15

The triploid East African Highland Banana (EAHB) genepool is genetically uniform arising from a single ancestral clone that underwent population expansion by vegetative propagation

Mercy Kitavi, Tim Downing, Jim Lorenzen, +5

Theoretical and Applied Genetics

BiologyGenetic DiversityMolecular EcologySingle Ancestral CloneComparative Genomics +11