Concepedia

Mohammed Alshahrani

MA

Statistics

Publications

8

Citations

173

H-Index

8

Active since

2023

Affiliations

Chapman University(Current)

Southern Methodist University

University of California San Diego

Mohammed Alshahrani is an author at Chapman University specializing in life sciences, molecular biology, and structural biology.

Publications per year

2023–2024

8

Publications

8

Markov State Models and Perturbation-Based Approaches Reveal Distinct Dynamic Signatures and Hidden Allosteric Pockets in the Emerging SARS-Cov-2 Spike Omicron Variant Complexes with the Host Receptor: The Interplay of Dynamics and Convergent Evolution Modulates Allostery and Functional Mechanisms

Sian Xiao, Mohammed Alshahrani, Grace Gupta et al. · Journal of Chemical Information and Modeling · 2023 · 43 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +17

AlphaFold2 Modeling and Molecular Dynamics Simulations of the Conformational Ensembles for the SARS-CoV-2 Spike Omicron JN.1, KP.2 and KP.3 Variants: Mutational Profiling of Binding Energetics Reveals Epistatic Drivers of the ACE2 Affinity and Escape Hotspots of Antibody Resistance

Nishank Raisinghani, Mohammed Alshahrani, Grace Gupta et al. · Viruses · 2024 · 28 citations · Full text

Life Sciences, Biology, Infectious Diseases +17

Balancing Functional Tradeoffs between Protein Stability and ACE2 Binding in the SARS-CoV-2 Omicron BA.2, BA.2.75 and XBB Lineages: Dynamics-Based Network Models Reveal Epistatic Effects Modulating Compensatory Dynamic and Energetic Changes

Gennady M. Verkhivker, Mohammed Alshahrani, Grace Gupta · Viruses · 2023 · 27 citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +17

AlphaFold2 Predictions of Conformational Ensembles and Atomistic Simulations of the SARS-CoV-2 Spike XBB Lineages Reveal Epistatic Couplings between Convergent Mutational Hotspots that Control ACE2 Affinity

Nishank Raisinghani, Mohammed Alshahrani, Grace Gupta et al. · The Journal of Physical Chemistry B · 2024 · 17 citations

Life Sciences, Biology, Molecular Biology +17

Probing conformational landscapes of binding and allostery in the SARS-CoV-2 omicron variant complexes using microsecond atomistic simulations and perturbation-based profiling approaches: hidden role of omicron mutations as modulators of allosteric signaling and epistatic relationships

Gennady M. Verkhivker, Mohammed Alshahrani, Grace Gupta et al. · Physical Chemistry Chemical Physics · 2023 · 16 citations · Full text

Life Sciences, Biology, Molecular Biology +17

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