Concepedia

Nishank Raisinghani

NR

Statistics

Publications

5

Citations

87

H-Index

5

Active since

2024

Affiliations

Chapman University(Current)

Southern Methodist University

Nishank Raisinghani is an author at Chapman University specializing in life sciences, biology, and protein-protein interaction modeling.

ORCID

Publications per year

2024–2024

5

Publications

5

AlphaFold2 Modeling and Molecular Dynamics Simulations of the Conformational Ensembles for the SARS-CoV-2 Spike Omicron JN.1, KP.2 and KP.3 Variants: Mutational Profiling of Binding Energetics Reveals Epistatic Drivers of the ACE2 Affinity and Escape Hotspots of Antibody Resistance

Nishank Raisinghani, Mohammed Alshahrani, Grace Gupta et al. · Viruses · 2024 · 28 citations · Full text

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AlphaFold2 Predictions of Conformational Ensembles and Atomistic Simulations of the SARS-CoV-2 Spike XBB Lineages Reveal Epistatic Couplings between Convergent Mutational Hotspots that Control ACE2 Affinity

Nishank Raisinghani, Mohammed Alshahrani, Grace Gupta et al. · The Journal of Physical Chemistry B · 2024 · 17 citations

, , +17

Ensemble-Based Mutational Profiling and Network Analysis of the SARS-CoV-2 Spike Omicron XBB Lineages for Interactions with the ACE2 Receptor and Antibodies: Cooperation of Binding Hotspots in Mediating Epistatic Couplings Underlies Binding Mechanism and Immune Escape

Nishank Raisinghani, Mohammed Alshahrani, Grace Gupta et al. · International Journal of Molecular Sciences · 2024 · 16 citations · Full text

, , +17

Integration of a Randomized Sequence Scanning Approach in AlphaFold2 and Local Frustration Profiling of Conformational States Enable Interpretable Atomistic Characterization of Conformational Ensembles and Detection of Hidden Allosteric States in the ABL1 Protein Kinase

Nishank Raisinghani, Mohammed Alshahrani, Grace Gupta et al. · Journal of Chemical Theory and Computation · 2024 · 14 citations · Full text

, , +15

Exploring conformational landscapes and binding mechanisms of convergent evolution for the SARS-CoV-2 spike Omicron variant complexes with the ACE2 receptor using AlphaFold2-based structural ensembles and molecular dynamics simulations

Nishank Raisinghani, Mohammed Alshahrani, Grace Gupta et al. · Physical Chemistry Chemical Physics · 2024 · 12 citations · Full text

, , +17

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