Hiroshi Shirota

A novel antagonist of the prostaglandin E₂ EP₄ receptor inhibits Th1 differentiation and Th17 expansion and is orally active in arthritis models

Q Chen, Kazuyo Muramoto, Nagashima Masaaki et al. · British Journal of Pharmacology · 2010 · 94 citations · Full text

Synthesis and antiinflammatory activities of 3-(3,5-di-tert-butyl-4-hydroxybenzylidene)pyrrolidin-2-ones

Hironori Ikuta, Hiroshi Shirota, Shigeya Kobayashi et al. · Journal of Medicinal Chemistry · 1987 · 74 citations

Pharmaceutical Science, Bioorganic Chemistry, Candidate Drug +17

Antitumor effects of eribulin depend on modulation of the tumor microenvironment by vascular remodeling in mouse models

Ken Ito, Shusei Hamamichi, Takanori Abe et al. · Cancer Science · 2017 · 68 citations · Full text

E6201 [(3S,4R,5Z,8S,9S,11E)-14-(Ethylamino)-8, 9,16-trihydroxy-3,4-dimethyl-3,4,9,19-tetrahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione], a Novel Kinase Inhibitor of Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Kinase (MEK)-1 and MEK Kinase-1: In Vitro Characterization of Its Anti-Inflammatory and Antihyperproliferative Activities

Masaki Goto, Jesse C. Chow, Kenzo Muramoto et al. · Journal of Pharmacology and Experimental Therapeutics · 2009 · 52 citations

Comparison of Tl-201 chloride and Ga-67 citrate scintigraphy in the diagnosis of thyroid tumor: concise communication.

O Senga, Makoto Miyakawa, Hiroshi Shirota et al. · PubMed · 1982 · 44 citations

Tl-201 Chloride, Thyroid Tumors, Ga-67 Citrate Scintigraphy +12