Iris Nira Smith

Conformational Dynamics and Allosteric Regulation Landscapes of Germline PTEN Mutations Associated with Autism Compared to Those Associated with Cancer

Iris Nira Smith, Stetson Thacker, Marilyn Seyfi et al. · The American Journal of Human Genetics · 2019 · 66 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

The mechanism of full activation of tumor suppressor PTEN at the phosphoinositide-enriched membrane

Hyunbum Jang, Iris Nira Smith, Charis Eng et al. · iScience · 2021 · 64 citations · Full text

Life Sciences, Molecular Biology, Oncology +16

Structural mutation analysis of PTEN and its genotype‐phenotype correlations in endometriosis and cancer

Iris Nira Smith, James M. Briggs · Proteins Structure Function and Bioinformatics · 2016 · 57 citations · Full text

Life Sciences, Genetics, Molecular Biology +16

Dynamics and structural stability effects of germline <i>PTEN</i> mutations associated with cancer versus autism phenotypes

Iris Nira Smith, Stetson Thacker, Ritika Jaini et al. · Journal of Biomolecular Structure and Dynamics · 2018 · 50 citations

Life Sciences, Genetics, Molecular Genetics +17

Structural and Dynamic Effects of PTEN C-Terminal Tail Phosphorylation

Iris Nira Smith, Jennifer E. Dawson, James Krieger et al. · Journal of Chemical Information and Modeling · 2022 · 19 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15