Lewis Mervin

Reinvent 4: Modern AI–driven generative molecule design

Hannes H. Loeffler, Jiazhen He, Alessandro Tibo et al. · Journal of Cheminformatics · 2024 · 183 citations · Full text

Trisubstituted-Imidazoles Induce Apoptosis in Human Breast Cancer Cells by Targeting the Oncogenic PI3K/Akt/mTOR Signaling Pathway

Chakrabhavi Dhananjaya Mohan, Venkatachalaiah Srinivasa, Shobith Rangappa et al. · PLoS ONE · 2016 · 130 citations · Full text

Medicinal Chemistry, Trisubstituted-imidazoles Induce Apoptosis, Akt2 Kinase +15

Target prediction utilising negative bioactivity data covering large chemical space

Lewis Mervin, Avid M. Afzal, Georgios Drakakis et al. · Journal of Cheminformatics · 2015 · 128 citations · Full text

JUMP Cell Painting dataset: morphological impact of 136,000 chemical and genetic perturbations

Srinivas Niranj Chandrasekaran, Jeanelle Ackerman, Eric Alix et al. · 2023 · 95 citations · Full text

Engineering, Genetics, Digital Pathology +24

MELLODDY: Cross-pharma Federated Learning at Unprecedented Scale Unlocks Benefits in QSAR without Compromising Proprietary Information

Wouter Heyndrickx, Lewis Mervin, Tobias Morawietz et al. · Journal of Chemical Information and Modeling · 2023 · 94 citations · Full text

Engineering, Machine Learning, Machine Learning Tool +19