Renee Hrin

Addition of a cholesterol group to an HIV-1 peptide fusion inhibitor dramatically increases its antiviral potency

Paolo Ingallinella, Elisabetta Bianchi, Neal A. Ladwa et al. · Proceedings of the National Academy of Sciences · 2009 · 211 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +14

A human monoclonal antibody neutralizes diverse HIV-1 isolates by binding a critical gp41 epitope

Michael D. Miller, Romas Geleziunas, Elisabetta Bianchi et al. · Proceedings of the National Academy of Sciences · 2005 · 156 citations

Pharmacy, Immunology, Molecular Biology +17

Potent 1,3,4-trisubstituted pyrrolidine CCR5 receptor antagonists: effects of fused heterocycles on antiviral activity and pharmacokinetic properties

Dooseop Kim, Liping Wang, Jeffrey J. Hale et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 149 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

Structural basis for HIV-1 neutralization by a gp41 fusion intermediate–directed antibody

Micah A. Luftig, Marco Mattu, Paolo Di Giovine et al. · Nature Structural & Molecular Biology · 2006 · 129 citations

Pharmacy, Immunology, Molecular Biology +16

An oligosaccharide-based HIV-1 2G12 mimotope vaccine induces carbohydrate-specific antibodies that fail to neutralize HIV-1 virions

Joseph G. Joyce, Isaac J. Krauss, Hong Chang Song et al. · Proceedings of the National Academy of Sciences · 2008 · 128 citations · Full text

Life Sciences, Immunology, Molecular Biology +17