Insights into Egg Coat Assembly and Egg-Sperm Interaction from the X-Ray Structure of Full-Length ZP3

Ling Han, Magnus Monné, Hiroki Okumura, +5

Cell

X-ray CrystallographySpermatogenesisMaterials ScienceDevelopmental BiologyEngineering +10

Structural Basis of the Human Endoglin-BMP9 Interaction: Insights into BMP Signaling and HHT1

Takako Saitô, Marcel Bokhove, Romina Croci, +5

Cell Reports

Crystal structure of the ZP-N domain of ZP3 reveals the core fold of animal egg coats

Magnus Monné, Ling Han, Thomas Schwend, +2

Nature

Crystal StructureMedicineCore FoldMolecular BiologyStructural Biology +3

The serine protease hepsin mediates urinary secretion and polymerisation of Zona Pellucida domain protein uromodulin

Martina Brunati, Simone Perucca, Ling Han, +16

eLife

Protein ChemistryUromodulin ProcessingProtein SecretionMolecular PhysiologyProtein Function +12

Structural Basis of Egg Coat-Sperm Recognition at Fertilization

Isha Raj, Hamed Sadat Al Hosseini, Elisa Dioguardi, +5

Cell

A structured interdomain linker directs self-polymerization of human uromodulin

Marcel Bokhove, Kaoru Nishimura, Martina Brunati, +4

Proceedings of the National Academy of Sciences

Molecular basis of egg coat cross-linking sheds light on ZP1-associated female infertility

Kaoru Nishimura, Elisa Dioguardi, Shunsuke Nishio, +4

Nature Communications

Easy mammalian expression and crystallography of maltose-binding protein-fused human proteins

Marcel Bokhove, Hamed Sadat Al Hosseini, Takako Saitô, +7

Journal of Structural Biology

Cryo‐EM structure of native human uromodulin, a zona pellucida module polymer

Alena Stsiapanava, Chenrui Xu, Martina Brunati, +10

The EMBO Journal

The C-terminal region of OVGP1 remodels the zona pellucida and modifies fertility parameters

Blanca Algarra, Ling Han, Cristina Soriano‐Úbeda, +4

Scientific Reports