Luke Green

Discovery of Risdiplam, a Selective Survival of Motor Neuron-2 ( <i>SMN2</i> ) Gene Splicing Modifier for the Treatment of Spinal Muscular Atrophy (SMA)

Hasane Ratni, Martin Ebeling, John D. Baird et al. · Journal of Medicinal Chemistry · 2018 · 520 citations · Full text

Medicine, Neurology, Pharmacology +14

An orally active chemokine receptor CCR2 antagonist prevents glomerulosclerosis and renal failure in type 2 diabetes

Sufyan G. Sayyed, Mi Heon Ryu, Onkar P. Kulkarni et al. · Kidney International · 2011 · 127 citations · Full text

Medicine, Nephrology, Pharmacotherapy +14

Specific Correction of Alternative Survival Motor Neuron 2 Splicing by Small Molecules: Discovery of a Potential Novel Medicine To Treat Spinal Muscular Atrophy

Hasane Ratni, Gary M. Karp, Marla Weetall et al. · Journal of Medicinal Chemistry · 2016 · 113 citations

Life Sciences, Molecular Biology, Neuroscience +14

One-pot Synthesis of Penta- and Hepta-saccharides from Monomeric Mannose Building Blocks Using the Principles of Orthogonality and Reactivity Tuning

Luke Green, Berthold Hinzen, Stuart J. Ince et al. · Synlett · 1998 · 51 citations

Life Sciences, Biochemistry, Chemistry +16

JAK and mTOR inhibitors prevent cytokine release while retaining T cell bispecific antibody in vivo efficacy

Gabrielle Leclercq-Cohen, Hélène Haegel, Alberto Toso et al. · Journal for ImmunoTherapy of Cancer · 2022 · 35 citations · Full text

Medicine, Immunology, Pharmacology +17