Lee M. Booty

Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1

Evanna L. Mills, Dylan G. Ryan, Hiran A. Prag et al. · Nature · 2018 · 1.8K citations

Life Sciences, Biochemistry, Cell Biology +12

Macrophage-Derived Extracellular Succinate Licenses Neural Stem Cells to Suppress Chronic Neuroinflammation

Luca Peruzzotti‐Jametti, Joshua D. Bernstock, Nunzio Vicario et al. · Cell stem cell · 2018 · 276 citations · Full text

Life Sciences, Neurobiology, Neuroscience +14

<i>Salmonella</i> Flagellin Activates NAIP/NLRC4 and Canonical NLRP3 Inflammasomes in Human Macrophages

Anna M. Gram, John A. Wright, Robert J. Pickering et al. · The Journal of Immunology · 2020 · 104 citations · Full text

Life Sciences, Infectious Diseases, Microbiology +17

The mitochondrial dicarboxylate and 2‐oxoglutarate carriers do not transport glutathione

Lee M. Booty, Martin King, Chancievan Thangaratnarajah et al. · FEBS Letters · 2015 · 65 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Ester Prodrugs of Malonate with Enhanced Intracellular Delivery Protect Against Cardiac Ischemia-Reperfusion Injury In Vivo

Hiran A. Prag, Laura Pala, Duvaraka Kula‐Alwar et al. · Cardiovascular Drugs and Therapy · 2020 · 55 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14