Eugen Lounkine

Large-scale prediction and testing of drug activity on side-effect targets

Eugen Lounkine, Michael J. Keiser, Steven Whitebread et al. · Nature · 2012 · 878 citations · Full text

Systems Pharmacology, Drug Activity, Drug Target +9

Discovery of Orally Active Inhibitors of Brahma Homolog (BRM)/SMARCA2 ATPase Activity for the Treatment of Brahma Related Gene 1 (BRG1)/SMARCA4-Mutant Cancers

Julien P. N. Papillon, Katsumasa Nakajima, Christopher D. Adair et al. · Journal of Medicinal Chemistry · 2018 · 225 citations · Full text

Brahma Homolog, Molecular Biology, Cancer Biology +19

Identifying mechanism-of-action targets for drugs and probes

Elisabet Gregori‐Puigjané, Vincent Setola, Jérôme Hert et al. · Proceedings of the National Academy of Sciences · 2012 · 176 citations · Full text

Rethinking Molecular Similarity: Comparing Compounds on the Basis of Biological Activity

Paula Petrone, B. T. Simms, Florian Nigsch et al. · ACS Chemical Biology · 2012 · 158 citations

Dark chemical matter as a promising starting point for drug lead discovery

Anne Mai Wassermann, Eugen Lounkine, Dominic Hoepfner et al. · Nature Chemical Biology · 2015 · 133 citations

Drug Target, Hit Identification, Dark Chemical Matter +8