Concepedia
Statistics
Publications
14
Citations
645
H-Index
13
Active since
2011
Affiliations
Leiden University(Current)
Centre for Human Drug Research
Erasmus MC
Erasmus University Rotterdam
Leiden University Medical Center
Kuan Yan is an author at Leiden University specializing in cell biology, life sciences, and medicine.
Publications per year
2011–2022
Functional patient-derived organoid screenings identify MCLA-158 as a therapeutic EGFR × LGR5 bispecific antibody with efficacy in epithelial tumors
Bram Herpers, Berina Eppink, Mark I. James et al. · Nature Cancer · 2022 · 159 citations · Full text
Medicine, Cancer Biology, Oncology +14
Annexin A2 depletion delays EGFR endocytic trafficking via cofilin activation and enhances EGFR signaling and metastasis formation
Marjo de Graauw, Lu Cao, Leah C.J. Winkel et al. · Oncogene · 2013 · 65 citations
Life Sciences, Cell Biology, Molecular Biology +16
Differential reprogramming of breast cancer subtypes in 3D cultures and implications for sensitivity to targeted therapy
Esmee Koedoot, Liesanne Wolters, Marcel Smid et al. · Scientific Reports · 2021 · 57 citations · Full text
Life Sciences, Cell Biology, Oncology +17
Identification of anti-tumour biologics using primary tumour models, 3-D phenotypic screening and image-based multi-parametric profiling
Alan M. Sandercock, Steven Rust, Sandrine Guillard et al. · Molecular Cancer · 2015 · 53 citations · Full text
Medicine, Cell Biology, Oncology +17
Cellular adhesome screen identifies critical modulators of focal adhesion dynamics, cellular traction forces and cell migration behaviour
Michiel Fokkelman, Hayri E. Balcıoğlu, Janna E. Klip et al. · Scientific Reports · 2016 · 50 citations · Full text
1–5 of 14