Jan‐Ytzen van der Meer

Using mutability landscapes of a promiscuous tautomerase to guide the engineering of enantioselective Michaelases

Jan‐Ytzen van der Meer, Harshwardhan Poddar, Bert‐Jan Baas et al. · Nature Communications · 2016 · 105 citations · Full text

Natural Sciences, Biochemistry, Chemistry +17

Enantioselective Synthesis of Pharmaceutically Active γ-Aminobutyric Acids Using a Tailor-Made Artificial Michaelase in One-Pot Cascade Reactions

Lieuwe Biewenga, Thangavelu Saravanan, Andreas Kunzendorf et al. · ACS Catalysis · 2019 · 69 citations · Full text

Engineering, Medicinal Chemistry, Pharmacology +14

Aqueous Oxidative Heck Reaction as a Protein‐Labeling Strategy

Maria E. Ourailidou, Jan‐Ytzen van der Meer, Bert‐Jan Baas et al. · ChemBioChem · 2013 · 47 citations · Full text

Life Sciences, Biochemistry, Biotechnology +12

Mutations Closer to the Active Site Improve the Promiscuous Aldolase Activity of 4‐Oxalocrotonate Tautomerase More Effectively than Distant Mutations

Mehran Rahimi, Jan‐Ytzen van der Meer, Edzard M. Geertsema et al. · ChemBioChem · 2016 · 21 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Inter- and intramolecular aldol reactions promiscuously catalyzed by a proline-based tautomerase

Mehran Rahimi, Edzard M. Geertsema, Yufeng Miao et al. · Organic & Biomolecular Chemistry · 2017 · 20 citations · Full text

Life Sciences, Biochemistry, Chemistry +17