Andreas Kunzendorf

Using mutability landscapes of a promiscuous tautomerase to guide the engineering of enantioselective Michaelases

Jan‐Ytzen van der Meer, Harshwardhan Poddar, Bert‐Jan Baas et al. · Nature Communications · 2016 · 105 citations · Full text

Natural Sciences, Biochemistry, Chemistry +17

Enantioselective Synthesis of Pharmaceutically Active γ-Aminobutyric Acids Using a Tailor-Made Artificial Michaelase in One-Pot Cascade Reactions

Lieuwe Biewenga, Thangavelu Saravanan, Andreas Kunzendorf et al. · ACS Catalysis · 2019 · 69 citations · Full text

Engineering, Medicinal Chemistry, Pharmacology +14

Unlocking Asymmetric Michael Additions in an Archetypical Class I Aldolase by Directed Evolution

Andreas Kunzendorf, Guangcai Xu, Jesse J. H. van der Velde et al. · ACS Catalysis · 2021 · 48 citations · Full text

Life Sciences, Biochemistry, Biotechnology +17

Biocatalytic Asymmetric Cyclopropanations via Enzyme‐Bound Iminium Ion Intermediates

Andreas Kunzendorf, Guangcai Xu, Mohammad Saifuddin et al. · Angewandte Chemie International Edition · 2021 · 35 citations · Full text

Natural Sciences, Biochemistry, Chemistry +17

Gene Fusion and Directed Evolution to Break Structural Symmetry and Boost Catalysis by an Oligomeric C−C Bond‐Forming Enzyme

Guangcai Xu, Andreas Kunzendorf, Michele Crotti et al. · Angewandte Chemie International Edition · 2021 · 35 citations · Full text

Engineering, Biotechnology, Chemistry +17